Prepubescent female rodents have enhanced hippocampal LTP and learning relative to males, reversing in adulthood as inhibition increases.
Sign Up to like & getrecommendations! Published in 2022 at "Nature neuroscience"
DOI: 10.1038/s41593-021-01001-5
Abstract: Multiple studies indicate that adult male rodents perform better than females on spatial problems and have a lower threshold for long-term potentiation (LTP) of hippocampal CA3-to-CA1 synapses. We report here that, in rodents, prepubescent females… read more here.
Keywords: female rodents; prepubescent female; ltp; hippocampal ltp ... See more keywords
5‐HT3A receptors maintain hippocampal LTP in a CB1 and GABAA receptor‐ dependent manner for spatial memory
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15793
Abstract: As the only ionotropic receptor in the 5‐HT receptor family, the 5‐HT3 receptor (5‐HT3R) is involved in psychiatric disorders and its modulators have potential therapeutic effects for cognitive impairment in these disorders. However, it remains… read more here.
Keywords: hippocampal ltp; ht3a receptors; receptors maintain; memory ... See more keywords
Circadian Regulation by REV-ERBα Mediates Hippocampal E-LTP in a Time-dependent Manner
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Neurobiology"
DOI: 10.5607/en.2018.27.5.344
Abstract: Circadian rhythms are driven by circadian oscillators, and these rhythms result in the biological phenomenon of 24-h oscillations. Previous studies suggest that learning and memory are affected by circadian rhythms. One of the genes responsible… read more here.
Keywords: rev erb; time dependent; rev; hippocampal ltp ... See more keywords