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   Articles with "hippocampal neuronal" as a keyword



Ferritin reduction is essential for cerebral ischemia-induced hippocampal neuronal death through p53/SLC7A11-mediated ferroptosis

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recommendations! Published in 2021 at "Brain Research"

DOI: 10.1016/j.brainres.2020.147216

Abstract: Cerebral ischemia is the most common cause of hippocampal neuronal death and the most prevalent cause of stroke with high mortality rate. Ferroptosis has been suggested to affect the role of hippocampal neurons. This study… read more here.

Keywords: hippocampal neuronal; cerebral ischemia; neuronal death; p53 slc7a11 ... See more keywords

Influence of tetramethylenedisulfotetramine on synchronous calcium oscillations at distinct developmental stages of hippocampal neuronal cultures

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recommendations! Published in 2017 at "Neurotoxicology"

DOI: 10.1016/j.neuro.2016.10.015

Abstract: HighlightsHippocampal neuronal cultures (HN) and neuron/glia co‐cultures (HNG) form networks.HN and HNA networks show spontaneous synchronous Ca2+oscillations (SCO).HN and HNG display distinct SCO patterns during development.The developmental patterns of SCO in HN and HNG may… read more here.

Keywords: hippocampal neuronal; hng; frequency; neuronal cultures ... See more keywords
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Enantioselectivity of 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) Atropisomers toward Ryanodine Receptors (RyRs) and Their Influences on Hippocampal Neuronal Networks.

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recommendations! Published in 2017 at "Environmental science & technology"

DOI: 10.1021/acs.est.7b04446

Abstract: Nineteen ortho-substituted PCBs are chiral and found enantioselectively enriched in ecosystems. Their differential actions on biological targets are not understood. PCB 95 (2,2',3,5',6-pentachlorobiphenyl), a chiral PCB of current environmental relevance, is among the most potent… read more here.

Keywords: hippocampal neuronal; pcb; ryanodine receptors; enantioselectivity pentachlorobiphenyl ... See more keywords
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Metabolic Regulation of Hippocampal Neuronal Development and Its Inhibition After Irradiation.

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recommendations! Published in 2021 at "Journal of neuropathology and experimental neurology"

DOI: 10.1093/jnen/nlab014

Abstract: 5'-Adenosine monophosphate-activated protein kinase (AMPK), a key regulator of cellular energy homeostasis, plays a role in cell fate determination. Whether AMPK regulates hippocampal neuronal development remains unclear. Hippocampal neurogenesis is abrogated after DNA damage. Here,… read more here.

Keywords: hippocampal neuronal; irradiation; inhibition; ampk ... See more keywords
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Effects of 1950 MHz radiofrequency electromagnetic fields on Aβ processing in human neuroblastoma and mouse hippocampal neuronal cells

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recommendations! Published in 2018 at "Journal of Radiation Research"

DOI: 10.1093/jrr/rrx045

Abstract: Abstract Alzheimer’s disease (AD) is a neurodegenerative disease leading to progressive loss of memory and other cognitive functions. One of the well-known pathological markers of AD is the accumulation of amyloid-beta protein (Aβ), and its… read more here.

Keywords: radiofrequency electromagnetic; hippocampal neuronal; electromagnetic fields; mhz ... See more keywords
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Astrocyte-mediated Transduction of Muscle Fiber Contractions Synchronizes Hippocampal Neuronal Network Development

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recommendations! Published in 2022 at "Neuroscience"

DOI: 10.1101/2022.04.12.487995

Abstract: Exercise supports brain health in part through enhancing hippocampal function. The leading hypothesis is that muscles release factors when they contract (e.g., lactate, myokines, growth factors) that enter circulation and reach the brain where they… read more here.

Keywords: network; hippocampal neuronal; network development; development ... See more keywords
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Formaldehyde induces ferritinophagy to damage hippocampal neuronal cells.

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recommendations! Published in 2021 at "Toxicology and industrial health"

DOI: 10.1177/07482337211048582

Abstract: Formaldehyde (FA) causes neurotoxicity and contributes to the occurrence of neurodegenerative diseases. However, the mechanism of FA-induced neurotoxicity has not been fully elucidated. Ferritinophagy, an autophagy process of ferritin mediated by the nuclear receptor coactivator… read more here.

Keywords: induces ferritinophagy; hippocampal neuronal; formaldehyde induces; ferritinophagy damage ... See more keywords
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Pannexin 1 activity in astroglia sets hippocampal neuronal network patterns

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recommendations! Published in 2022 at "PLOS Biology"

DOI: 10.1371/journal.pbio.3001891

Abstract: Astroglial release of molecules is thought to actively modulate neuronal activity, but the nature, release pathway, and cellular targets of these neuroactive molecules are still unclear. Pannexin 1, expressed by neurons and astrocytes, form nonselective… read more here.

Keywords: hippocampal neuronal; pannexin; activity; astroglial pannexin ... See more keywords
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Telmisartan, an Antagonist of Angiotensin II Receptors, Accentuates Voltage-Gated Na+ Currents and Hippocampal Neuronal Excitability

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recommendations! Published in 2020 at "Frontiers in Neuroscience"

DOI: 10.3389/fnins.2020.00902

Abstract: Telmisartan (TEL), a non-peptide blocker of the angiotensin II type 1 receptor, is a widely used antihypertensive agent. Nevertheless, its neuronal ionic effects and how they potentially affect neuronal network excitability remain largely unclear. With… read more here.

Keywords: hippocampal neuronal; neuronal excitability; tel; ina ... See more keywords
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Quantitative omics analyses of NCOA4 deficiency reveal an integral role of ferritinophagy in iron homeostasis of hippocampal neuronal HT22 cells

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recommendations! Published in 2023 at "Frontiers in Nutrition"

DOI: 10.3389/fnut.2023.1054852

Abstract: Introduction Neurons require iron to support their metabolism, growth, and differentiation, but are also susceptible to iron-induced oxidative stress and cytotoxicity. Ferritin, a cytosolic iron storage unit, mediates cellular adaptation to fluctuations in iron delivery.… read more here.

Keywords: hippocampal neuronal; ht22 cells; iron; ncoa4 deficiency ... See more keywords
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Effects of Protocatechuic Acid (PCA) on Global Cerebral Ischemia-Induced Hippocampal Neuronal Death

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recommendations! Published in 2018 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms19051420

Abstract: Global cerebral ischemia (GCI) is one of the main causes of hippocampal neuronal death. Ischemic damage can be rescued by early blood reperfusion. However, under some circumstances reperfusion itself can trigger a cell death process… read more here.

Keywords: hippocampal neuronal; death; neuronal death; pca ... See more keywords