The role of replay and theta sequences in mediating hippocampal‐prefrontal interactions for memory and cognition
Sign Up to like & getrecommendations! Published in 2017 at "Hippocampus"
DOI: 10.1002/hipo.22821
Abstract: Sequential activity is seen in the hippocampus during multiple network patterns, prominently as replay activity during both awake and sleep sharp‐wave ripples (SWRs), and as theta sequences during active exploration. Although various mnemonic and cognitive… read more here.
Keywords: replay theta; prefrontal interactions; theta sequences; memory ... See more keywords
NMDA receptor antagonists traxoprodil and lanicemine improve hippocampal-prefrontal coupling and reward-related networks in rats
Sign Up to like & getrecommendations! Published in 2019 at "Psychopharmacology"
DOI: 10.1007/s00213-019-05310-3
Abstract: RationaleThe N-methyl-d-aspartate receptor (NMDAR) antagonist ketamine is known to have not only a rapid antidepressant effect but also dissociative side effects. Traxoprodil and lanicemine, also NMDA antagonists, are candidate antidepressant drugs with fewer side effects.ObjectivesIn… read more here.
Keywords: ketamine; connectivity; antidepressant effect; effect ... See more keywords
Automated dissection of permanent effects of hippocampal or prefrontal lesions on performance at spatial, working memory and circadian timing tasks of C57BL/6 mice in IntelliCage
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2017.08.048
Abstract: ABSTRACT To evaluate permanent effects of hippocampal and prefrontal cortex lesion on spatial tasks, lesioned and sham‐operated female C57BL/6 mice were exposed to a series of conditioning schemes in IntelliCages housing 8–10 transponder‐tagged mice from… read more here.
Keywords: c57bl mice; circadian timing; effects hippocampal; working memory ... See more keywords