Transient receptor potential vanilloid 4 activation inhibits the delayed rectifier potassium channels in hippocampal pyramidal neurons: An implication in pathological changes following pilocarpine‐induced status epilepticus
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24749
Abstract: Activation of transient receptor potential vanilloid 4 (TRPV4) can increase hippocampal neuronal excitability. TRPV4 has been reported to be involved in the pathogenesis of epilepsy. Voltage‐gated potassium channels (VGPCs) play an important role in regulating… read more here.
Keywords: receptor potential; pyramidal neurons; hippocampal pyramidal; transient receptor ... See more keywords
Hippocampal pyramidal cells of the CA1 region are not a major target of the thalamic nucleus reuniens
Sign Up to like & getrecommendations! Published in 2025 at "PLOS Biology"
DOI: 10.1371/journal.pbio.3003419
Abstract: The prefrontal—hippocampal—entorhinal system is perhaps the most widely-studied circuit in cognitive and systems neuroscience, due to its role in supporting cognitive functions such as working memory and decision-making. Disrupted communication within this circuit is a… read more here.
Keywords: thalamic nucleus; cells ca1; nucleus reuniens; pyramidal cells ... See more keywords
The spatio-temporal properties of calcium transients in hippocampal pyramidal neurons in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.1054950
Abstract: The spatio-temporal properties of calcium signals were studied in cultured pyramidal neurons of the hippocampus using two-dimensional fluorescence microscopy and ratiometric dye Fura-2. Depolarization-induced Ca2+ transients revealed an asynchronous delayed increase in free Ca2+ concentration.… read more here.
Keywords: pyramidal neurons; hippocampal pyramidal; depolarization; properties calcium ... See more keywords