Hippocampal sclerosis, TDP‐43, and the duration of the symptoms of dementia of AD patients
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DOI: 10.1002/acn3.51135
Abstract: To examine the relationship between duration of the cognitive symptoms, from the earliest reported symptom to death, and hippocampal sclerosis (HS) and TAR‐DNA binding protein of 43kDA (TDP‐43) in Alzheimer’s disease (AD) patients. read more here.
Keywords: hippocampal sclerosis; duration symptoms; duration; tdp duration ... See more keywords
Diffusion spectrum imaging predicts hippocampal sclerosis in mesial temporal lobe epilepsy patients
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51503
Abstract: Epileptic patients suffer from seizure recurrence after surgery due to the challenging localization. Improvement of the noninvasive imaging‐based approach for a better definition of the abnormalities would be helpful for a better outcome. read more here.
Keywords: predicts hippocampal; sclerosis mesial; hippocampal sclerosis; imaging predicts ... See more keywords
Relative neuron loss in hippocampal sclerosis of aging and Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Neurology"
DOI: 10.1002/ana.25344
Abstract: To characterize the pattern of neuron loss in hippocampal sclerosis of aging (HS‐Aging) and age‐related diseases and to evaluate its contribution to cognitive impairment in the elderly. read more here.
Keywords: sclerosis aging; hippocampal sclerosis; loss hippocampal; neuron loss ... See more keywords
Glymphatic system dysfunction in temporal lobe epilepsy patients with hippocampal sclerosis
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DOI: 10.1002/epi4.12594
Abstract: This study aimed to evaluate glymphatic system function in temporal lobe epilepsy (TLE) patients with hippocampal sclerosis (HS) in comparison to healthy controls, using diffusion tensor imaging (DTI)‐analysis along the perivascular space (ALPS) method. We… read more here.
Keywords: system; patients hippocampal; lobe epilepsy; temporal lobe ... See more keywords
Coexistence of meningoencephalocele and hippocampal sclerosis: a new type of dual pathology
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-017-3153-9
Abstract: Both temporal lobe meningoencephalocele (TE) and hippocampal sclerosis (HS) are causes of drug-resistant temporal lobe epilepsy. Spontaneous TE constitutes a rare but well-known and increasingly recognised cause of refractory epilepsy. It is well known that… read more here.
Keywords: new type; hippocampal sclerosis; meningoencephalocele hippocampal; pathology ... See more keywords
Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109229
Abstract: Hippocampal sclerosis, the major neuropathological hallmark of temporal lobe epilepsy, is characterized by different patterns of neuronal loss. The mechanisms of cell-type-specific vulnerability and their progression and histopathological classification remain controversial. Using single-cell electrophysiology in vivo… read more here.
Keywords: type specific; cell; cell type; hippocampal sclerosis ... See more keywords
Hippocampal subfield measurement and ILAE hippocampal sclerosis subtype classification with in vivo 4.7 tesla MRI
Sign Up to like & getrecommendations! Published in 2020 at "Epilepsy Research"
DOI: 10.1016/j.eplepsyres.2020.106279
Abstract: OBJECTIVE Neuropathological studies indicate that hippocampal sclerosis (HS) consists of three subtypes (ILAE types 1-3 HS). However, HS subtypes currently can only be diagnosed by pathological analysis of hippocampal tissue resected during epilepsy surgery or… read more here.
Keywords: hippocampal sclerosis; hippocampus; vivo; hippocampal subfield ... See more keywords
Association of lewy bodies, hippocampal sclerosis and amyloid angiopathy with dementia in community-dwelling elderly: A systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2021.05.044
Abstract: INTRODUCTION We measured the proportion of Lewy body pathology (LB), hippocampal sclerosis (HS), and cerebral amyloid angiopathy (CAA) among community-dwelling people with and without dementia. METHODS We searched for community-based cohorts with postmortem brain autopsy… read more here.
Keywords: hippocampal sclerosis; dementia; community; pathology ... See more keywords
Clinical and pathological definition of temporal medium epilepsy subtypes with hypocampic sclerosis
Sign Up to like & getrecommendations! Published in 2017 at "Neurocirugia"
DOI: 10.1016/j.neucie.2017.12.002
Abstract: Abstract Background and objective Mesial temporal lobe epilepsy with hippocampal sclerosis is the most common cause of refractory epilepsy, and the most common indication for surgery. Although effective, surgery fails in up to 40% of… read more here.
Keywords: epilepsy; sclerosis; hippocampal sclerosis; neuronal loss ... See more keywords
Preservation of memory despite unresected contralateral hippocampal volume loss after resection of hippocampal sclerosis in seizure free patients.
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DOI: 10.1016/j.wneu.2019.08.021
Abstract: Objective To determine postoperative long-term changes of hippocampal volume (HV) correlating with cognitive functions in patients who underwent surgery for hippocampal sclerosis with postoperative freedom from seizures. Methods We studied 1.5T magnetic resonance imaging before… read more here.
Keywords: hippocampal sclerosis; volume; seizure; memory ... See more keywords
Executive Dysfunction and Depression in Pediatric Temporal Lobe Epilepsy: The Contribution of Hippocampal Sclerosis and Psychosocial Factors
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the International Neuropsychological Society"
DOI: 10.1017/s1355617718000140
Abstract: Abstract Objectives: Temporal lobe epilepsy (TLE) has been identified as a risk factor for increased depression features in children and adolescents; however, less is known regarding specific neurocognitive predictors of depression in this population above… read more here.
Keywords: lobe epilepsy; depression; hippocampal sclerosis; temporal lobe ... See more keywords