Region-dependent regulation of acute ethanol on γ oscillation in the rat hippocampal slices
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05584-y
Abstract: Ethanol use disorders are a serious medical and public health problem in the world today. Acute ethanol intoxication can lead to cognitive dysfunction such as learning and memory impairment. Gamma oscillations (γ, 30–80 Hz) are… read more here.
Keywords: hippocampus; oscillation; hippocampal slices; rat hippocampal ... See more keywords
Effect of Noopept on Dynamics of Intracellular Calcium in Neurons of Cultured Rat Hippocampal Slices
Sign Up to like & getrecommendations! Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-3983-3
Abstract: A neuroprotective and nootropic drug Noopept increased the frequency of spontaneous calcium transients in neurons of CA1 radial layer in cultured rat hippocampal slices. In contrast, the drug exerted no significant effect on intracellular calcium… read more here.
Keywords: intracellular calcium; rat hippocampal; hippocampal slices; calcium ... See more keywords
GABAA Modulation of S100B Secretion in Acute Hippocampal Slices and Astrocyte Cultures
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemical Research"
DOI: 10.1007/s11064-018-2675-8
Abstract: Astrocytes are the major glial cells in brain tissue and are involved, among many functions, ionic and metabolic homeostasis maintenance of synapses. These cells express receptors and transporters for neurotransmitters, including GABA. GABA signaling is… read more here.
Keywords: secretion; hippocampal slices; astrocyte cultures; slices astrocyte ... See more keywords
Analysis of respiratory capacity in brain tissue preparations: high-resolution respirometry for intact hippocampal slices.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2018.05.010
Abstract: The evaluation of mitochondrial function provides the basis for the study of brain bioenergetics. However, analysis of brain mitochondrial respiration has been hindered by the low yield associated with mitochondria isolation procedures. Furthermore, isolating mitochondria… read more here.
Keywords: methodology; high resolution; resolution respirometry; hippocampal slices ... See more keywords
Effect of priming low-frequency magnetic fields on zero-Mg2+ -induced epileptiform discharges in rat hippocampal slices
Sign Up to like & getrecommendations! Published in 2020 at "Epilepsy Research"
DOI: 10.1016/j.eplepsyres.2020.106464
Abstract: During the process of seizures, the addition of low-frequency magnetic fields has been proved to be an effective method to suppress epileptic discharges. However, whether adding magnetic fields before the appearance of epileptic discharges can… read more here.
Keywords: magnetic fields; frequency magnetic; frequency; hippocampal slices ... See more keywords
Enhanced LTP in aged rats: Detrimental or compensatory?
Sign Up to like & getrecommendations! Published in 2017 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2016.11.017
Abstract: ABSTRACT Age‐dependent memory deterioration has been well documented and yet an increase in rat hippocampal LTP upon aging has been reported. This poses the question of whether the enhanced LTP is a cause or an… read more here.
Keywords: aged rats; ltp; aged animals; compensatory ... See more keywords
Hydrogen sulfide inhibits giant depolarizing potentials and abolishes epileptiform activity of neonatal rat hippocampal slices
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2016.10.051
Abstract: Hydrogen sulfide (H2S) is an endogenous gasotransmitter with neuroprotective properties that participates in the regulation of transmitter release and neuronal excitability in various brain structures. The role of H2S in the growth and maturation of… read more here.
Keywords: giant depolarizing; hippocampal slices; depolarizing potentials; hydrogen sulfide ... See more keywords
Low-intensity ultrasound suppresses low-Mg2+-induced epileptiform discharges in juvenile mouse hippocampal slices.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of neural engineering"
DOI: 10.1088/1741-2552/ab0b9a
Abstract: OBJECTIVE It has been shown that low-intensity ultrasound (LIUS) can suppress seizures in some laboratory studies. However, the mechanism of the suppression effect of LIUS remains unclear. The goal of this study is to investigate… read more here.
Keywords: hippocampal slices; intensity ultrasound; epileptiform discharges; mouse hippocampal ... See more keywords
The Glycolytic Metabolite, Fructose-1,6-bisphosphate, Blocks Epileptiform Bursts by Attenuating Voltage-Activated Calcium Currents in Hippocampal Slices
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2018.00168
Abstract: Manipulation of metabolic pathways (e.g., ketogenic diet (KD), glycolytic inhibition) alters neural excitability and represents a novel strategy for treatment of drug-refractory seizures. We have previously shown that inhibition of glycolysis suppresses epileptiform activity in… read more here.
Keywords: fructose bisphosphate; activated calcium; hippocampal slices; voltage activated ... See more keywords
Human Dental Pulp Cells Differentiate toward Neuronal Cells and Promote Neuroregeneration in Adult Organotypic Hippocampal Slices In Vitro
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18081745
Abstract: The adult mammalian central nerve system has fundamental difficulties regarding effective neuroregeneration. The aim of this study is to investigate whether human dental pulp cells (DPCs) can promote neuroregeneration by (i) being differentiated toward neuronal… read more here.
Keywords: neuronal cells; adult; hippocampal slices; human dental ... See more keywords
Organotypic hippocampal slices, an emerging tool to model synucleinopathies
Sign Up to like & getrecommendations! Published in 2021 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.297065
Abstract: The pathological hallmark of PD is the presence of neuronal cytoplasmic inclusions called Lewy bodies (LB) or Lewy neurites, which consist of the abundant presynaptic protein alphasynuclein (α-syn) in an aggregated form. Apart from being… read more here.
Keywords: model synucleinopathies; slices emerging; hippocampal slices; organotypic hippocampal ... See more keywords