Effects of prenatal methamphetamine exposure on spatial cognition and hippocampal synaptic plasticity in adolescent rats
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Developmental Neuroscience"
DOI: 10.1002/jdn.10202
Abstract: Global rise in methamphetamine (MA) abuse during pregnancy has placed a large number of children at risk for the adverse consequences of prenatal methamphetamine exposure (PME). While behavioral and neurocognitive deficits of PME have been… read more here.
Keywords: pme; hippocampal synaptic; methamphetamine; synaptic plasticity ... See more keywords
Doxorubicin induces dysregulation of AMPA receptor and impairs hippocampal synaptic plasticity leading to learning and memory deficits
Sign Up to like & getrecommendations! Published in 2021 at "Heliyon"
DOI: 10.1016/j.heliyon.2021.e07456
Abstract: Doxorubicin (Dox) is a chemotherapeutic agent used widely to treat a variety of malignant cancers. However, Dox chemotherapy is associated with several adverse effects, including “chemobrain,” the observation that cancer patients exhibit through learning and… read more here.
Keywords: learning memory; hippocampal synaptic; dox; synaptic plasticity ... See more keywords
Mismatch novelty exploration training enhances hippocampal synaptic plasticity: A tool for cognitive stimulation?
Sign Up to like & getrecommendations! Published in 2017 at "Neurobiology of Learning and Memory"
DOI: 10.1016/j.nlm.2017.09.004
Abstract: HighlightsSpatial novelty training for two weeks influences rat hippocampal synaptic transmission.Spatial novelty training also enhances the expression of LTP evoked by theta‐burst stimulation.Spatial novelty training also enhances depotentiation evoked by low‐frequency stimulation.Training programs using spatial… read more here.
Keywords: stimulation; training; novelty; hippocampal synaptic ... See more keywords
Kappa opioid receptors regulate hippocampal synaptic homeostasis and epileptogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Epilepsia"
DOI: 10.1111/epi.13941
Abstract: Homeostatic synaptic plasticity (HSP) serves as a gain control mechanism at central nervous system (CNS) synapses, including those between the dentate gyrus (DG) and CA3. Improper circuit control of DG‐CA3 synapses is hypothesized to underlie… read more here.
Keywords: receptors regulate; epileptogenesis; hippocampal synaptic; opioid receptors ... See more keywords
Impact of blunting astrocyte activity on hippocampal synaptic plasticity in a mouse model of early Alzheimer's disease based on amyloid‐β peptide exposure
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.15575
Abstract: Amyloid‐β peptides (Aβ) accumulate in the brain since early Alzheimer's disease (AD) and dysregulate hippocampal synaptic plasticity, the neurophysiological basis of memory. Although the relationship between long‐term potentiation (LTP) and memory processes is well established,… read more here.
Keywords: early alzheimer; alzheimer disease; ltd; hippocampal synaptic ... See more keywords
Influence of Testosterone depletion on Neurotrophin-4 in Hippocampal synaptic plasticity and its effects on learning and memory.
Sign Up to like & getrecommendations! Published in 2022 at "Developmental neuroscience"
DOI: 10.1159/000522201
Abstract: Sex steroids are neuromodulators that play a crucial role in learning, memory, and synaptic plasticity, providing circuit flexibility and dynamic functional connectivity in mammals. Previous studies indicate that testosterone is crucial for neuronal functions and… read more here.
Keywords: testosterone; synaptic plasticity; memory; learning memory ... See more keywords
Maternal high fat diet multigenerationally impairs hippocampal synaptic plasticity and memory in male rat offspring.
Sign Up to like & getrecommendations! Published in 2020 at "Endocrinology"
DOI: 10.1210/endocr/bqaa214
Abstract: With advance of the developmental origins of health and disease, long-term influence of maternal environmental factors on offspring health is emphasized. Maternal high-fat diet (HFD) consumption has been suggested to exert detrimental effects on cognitive… read more here.
Keywords: hfd; maternal high; hippocampal synaptic; synaptic plasticity ... See more keywords
Geraniol improves passive avoidance memory and hippocampal synaptic plasticity deficits in a rat model of Alzheimer's disease.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of pharmacology"
DOI: 10.2139/ssrn.4289997
Abstract: Alzheimer's disease (AD) is the most progressive and irreversible neurodegenerative disease that leads to synaptic loss and cognitive decline. The present study was designed to evaluate the effects of geraniol (GR), a valuable acyclic monoterpene… read more here.
Keywords: passive avoidance; avoidance; hippocampal synaptic; avoidance memory ... See more keywords
Genetic Background Influence on Hippocampal Synaptic Plasticity: Frequency-Dependent Variations between an Inbred and an Outbred Mice Strain
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24054304
Abstract: For almost half a century, acute hippocampal slice preparations have been widely used to investigate anti-amnesic (or promnesic) properties of drug candidates on long-term potentiation (LTP)—a cellular substrate that supports some forms of learning and… read more here.
Keywords: inbred outbred; frequency; hippocampal synaptic; genetic background ... See more keywords