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Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2507
Abstract: Stress‐related brain disorders can be associated with glucocorticoid disturbance and hippocampal alteration. However, it remains largely unknown how cortisol affects the structure and function of hippocampus. Cushing's disease (CD) provides a unique “hyperexpression model” to…
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Keywords:
disease;
hippocampal volume;
volume functional;
functional connectivity ... See more keywords
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Published in 2023 at "Brain and Behavior"
DOI: 10.1002/brb3.2863
Abstract: The causes of the neurodegenerative processes in Alzheimer's disease (AD) are not completely known. Recent studies have shown that white matter (WM) damage could be more severe and widespread than whole‐brain cortical atrophy and that…
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Keywords:
disease;
alzheimer disease;
whole brain;
hippocampal volume ... See more keywords
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Published in 2022 at "GeroScience"
DOI: 10.1007/s11357-022-00558-8
Abstract: The concept of age acceleration, the difference between biological age and chronological age, is of growing interest, particularly with respect to age-related disorders, such as Alzheimer's Disease (AD). Whilst studies have reported associations with AD…
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Keywords:
hippocampal volume;
age acceleration;
age;
epigenetic clocks ... See more keywords
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Published in 2018 at "Aging Clinical and Experimental Research"
DOI: 10.1007/s40520-018-1030-x
Abstract: BackgroundSeveral lines of research support associations between sleep and cognition in older adults. However, there is a paucity of data regarding sleep and cognition in nonagenarians and centenarians.AimsThe current study examined self-reported sleep quantity and…
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Keywords:
volume;
hippocampal volume;
duration;
volume cognition ... See more keywords
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Published in 2017 at "European Psychiatry"
DOI: 10.1016/j.eurpsy.2017.01.2061
Abstract: Objectives Structural neuroimaging studies have revealed a consistent pattern of volumetric reductions in both the hippocampus and the anterior cingulate cortex (ACC) of individuals with a major depressive episode (MDE). This study investigated hippocampal and…
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Keywords:
depression;
volume;
hippocampal volume;
mde ... See more keywords
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Published in 2019 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2018.10.363
Abstract: BACKGROUND Major depressive disorder (MDD) is a serious psychiatric illness with unclear pathophysiology. As one of the post-transcriptional regulators, prior research has indicated that miRNAs are involved in the pathophysiology of MDD. The aim of…
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Keywords:
hippocampal volume;
peripheral blood;
pmir chr11;
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Published in 2019 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2019.06.005
Abstract: BACKGROUND The hippocampus is important for memory processing. Several neuropsychiatric diseases including Alzheimer's disease are associated with reduced hippocampal volume, and further the hippocampus appears vulnerable to environmental insult. Air pollution has been associated with…
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Keywords:
hippocampal volume;
air pollution;
volume;
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Published in 2020 at "Neuroimage"
DOI: 10.1016/j.neuroimage.2020.117211
Abstract: Highlights • Evidence is mixed about whether hippocampal volume affects cognitive task performance.• This is particularly the case concerning individual differences in healthy people.• We collected structural MRI data from 217 healthy people.• They also…
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Keywords:
performance differences;
hippocampal volume;
performance;
volume explain ... See more keywords
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Published in 2022 at "Neurobiology of Stress"
DOI: 10.1016/j.ynstr.2022.100441
Abstract: Objective Improved understanding of the time course of neural changes associated with adolescent PTSD would elucidate the development of the disorder and could inform approaches to treatment. We compared hippocampal volumes and resting state functional…
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Keywords:
ptsd;
recent ptsd;
hippocampal volume;
treatment ... See more keywords
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Published in 2017 at "Psychological Medicine"
DOI: 10.1017/s0033291717003166
Abstract: Abstract Background Although there is extensive evidence that problematic alcohol use is associated with smaller hippocampal volume, the typical cross-sectional study design cannot determine whether hippocampal deviations reflect pre-existing liability toward problematic alcohol use or…
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Keywords:
use;
hippocampal volume;
problematic alcohol;
alcohol ... See more keywords
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Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms13624
Abstract: The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the…
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Keywords:
associated hippocampal;
novel genetic;
volume;
hippocampal volume ... See more keywords