Involvement of progranulin in modulating neuroinflammatory responses but not neurogenesis in the hippocampus of aged mice
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2017.05.003
Abstract: Abstract It is well established that adult neurogenesis in the hippocampus declines with age. Our previous studies have suggested that progranulin (PGRN) has a facilitative effect on hippocampal neurogenesis. We have also shown that PGRN… read more here.
Keywords: neuroinflammatory responses; hippocampus; neurogenesis; age ... See more keywords
Alzheimer-like pathology in the parietal cortex and hippocampus of aged donkeys
Sign Up to like & getrecommendations! Published in 2022 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2022.01.007
Abstract: Neurodegenerative disorders are gaining ever more importance in ageing populations of animals and people. Altered insulin signaling and type II diabetes have been linked to the development of Alzheimer's disease (AD) in humans and AD-like… read more here.
Keywords: hippocampus aged; pathology parietal; alzheimer like; pathology ... See more keywords