A comparison of mitochondrial toxicity of mephedrone on three separate parts of brain including hippocampus, cortex and cerebellum.
Sign Up to like & getrecommendations! Published in 2019 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2019.02.014
Abstract: Mephedrone (4-methylmethcathinone) is a new and popular drug of abuse and also widely available on the internet and still legal in some parts of the world. The central nervous system is the target of mephedrone… read more here.
Keywords: hippocampus cortex; brain; cortex cerebellum; mephedrone ... See more keywords
PPARγ activation improved learning and memory and attenuated oxidative stress in the hippocampus and cortex of aged rats
Sign Up to like & getrecommendations! Published in 2022 at "Physiological Reports"
DOI: 10.14814/phy2.15538
Abstract: Oxidative stress has an important role in brain aging and its consequences include cognitive decline and physiological disorders. Peroxisome proliferator‐activated receptor‐γ (PPARγ) activation has been suggested to decrease oxidative stress. In the current research, the… read more here.
Keywords: stress; pio; oxidative stress; ppar activation ... See more keywords
Blood-Brain Barrier Disruption and Perivascular Beta-Amyloid Accumulation in the Brain of Aged Rats with Spontaneous Hypertension: Evaluation with Dynamic Contrast-Enhanced Magnetic Resonance Imaging
Sign Up to like & getrecommendations! Published in 2018 at "Korean Journal of Radiology"
DOI: 10.3348/kjr.2018.19.3.498
Abstract: Objective Whether blood-brain barrier (BBB) disruption induced by chronic spontaneous hypertension is associated with beta-amyloid (Aβ) accumulation in the brain remains poorly understood. The purpose of this study was to investigate the relationship between BBB… read more here.
Keywords: hippocampus cortex; accumulation; disruption; accumulation brain ... See more keywords
Metabolomics Analysis of Hippocampus and Cortex in a Rat Model of Traumatic Brain Injury in the Subacute Phase
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2020.00876
Abstract: Traumatic brain injury (TBI) is a complex and serious disease as its multifaceted pathophysiological mechanisms remain vague. The molecular changes of hippocampal and cortical dysfunction in the process of TBI are poorly understood, especially their… read more here.
Keywords: hippocampus cortex; traumatic brain; rat model; brain injury ... See more keywords