Uhrf2 deletion impairs the formation of hippocampus-dependent memory by changing the structure of the dentate gyrus
Sign Up to like & getrecommendations! Published in 2017 at "Brain Structure and Function"
DOI: 10.1007/s00429-017-1512-1
Abstract: Ubiquitin-like with PHD and ring finger domains 2 (Uhrf2) is distributed in many brain regions, including the cortex and hippocampus. Decreased Uhrf2 expression is involved in neurodegenerative disease. A recent study showed Uhrf2 deletion impaired… read more here.
Keywords: dentate gyrus; hippocampus dependent; uhrf2 deletion; memory ... See more keywords
The SETD6 Methyltransferase Plays an Essential Role in Hippocampus-Dependent Memory Formation
Sign Up to like & getrecommendations! Published in 2020 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2019.05.022
Abstract: BACKGROUND Epigenetic mechanisms are critical for hippocampus-dependent memory formation. Building on previous studies that implicate the N-lysine methyltransferase SETD6 in the activation of nuclear factor-κB RELA (also known as transcription factor p65) as an epigenetic… read more here.
Keywords: memory formation; hippocampus dependent; memory; setd6 ... See more keywords
Effects of preweaning environmental enrichment on hippocampus-dependent learning and memory in developing rats
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2016.12.053
Abstract: Previous studies have shown that environmental enrichment (EE) improves learning and memory in adult animals. However, the effects of preweaning EE (preEE) on hippocampus-dependent learning and memory as well as its possible mechanisms are poorly… read more here.
Keywords: group; learning memory; hippocampus dependent; memory ... See more keywords
Dietary Methionine via Dose-Dependent Inhibition of Short-Chain Fatty Acid Production Capacity Contributed to a Potential Risk of Cognitive Dysfunction in Mice.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c04847
Abstract: High-methionine diets induce impaired learning and memory function, dementia-like neurodegeneration, and Alzheimer's disease, while low-methionine diets improve learning and memory function. We speculated that variations in intestinal microbiota may mediate these diametrically opposed effects; thus,… read more here.
Keywords: chain fatty; hippocampus dependent; methionine; fatty acid ... See more keywords
REM sleep–active MCH neurons are involved in forgetting hippocampus-dependent memories
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aax9238
Abstract: A brain pathway for active forgetting Sleep affects memories via several mechanisms. Izawa et al. identified a possible new pathway in the brain: REM sleep–active hypothalamic melanin-concentrating hormone (MCH)–producing neurons, which, among others, project to… read more here.
Keywords: rem sleep; mch; sleep active; mch neurons ... See more keywords
AhR Deletion Promotes Aberrant Morphogenesis and Synaptic Activity of Adult-Generated Granule Neurons and Impairs Hippocampus-Dependent Memory
Sign Up to like & getrecommendations! Published in 2018 at "eNeuro"
DOI: 10.1523/eneuro.0370-17.2018
Abstract: Visual Abstract Newborn granule cells are continuously produced in the subgranular zone of dentate gyrus throughout life. Once these cells mature, they integrate into pre-existing circuits modulating hippocampus-dependent memory. Subsequently, mechanisms controlling generation and maturation… read more here.
Keywords: dependent memory; function; hippocampus dependent; memory ahr ... See more keywords
The p75 neurotrophin receptor regulates cranial irradiation-induced hippocampus-dependent cognitive dysfunction
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.16492
Abstract: Cognitive deficits, characterized by progressive problems with hippocampus-dependent learning, memory and spatial processing, are the most serious complication of cranial irradiation. However, the underlying mechanisms remain obscure. The p75 neurotrophin receptor (p75NTR) is involved in… read more here.
Keywords: neurotrophin receptor; irradiation; hippocampus dependent; irradiation induced ... See more keywords
Dose and time-dependence of acute intermittent theta-burst stimulation on hippocampus-dependent memory in parkinsonian rats
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2023.1124819
Abstract: Background The treatment options for cognitive impairments in Parkinson’s disease (PD) are limited. Repetitive transcranial magnetic stimulation has been applied in various neurological diseases. However, the effect of intermittent theta-burst stimulation (iTBS) as a more… read more here.
Keywords: dependent memory; hippocampus dependent; stimulation; memory ... See more keywords