Neural circuitry among connecting the hippocampus, prefrontal cortex and basolateral amygdala in a mouse depression model: Associations correlations between BDNF levels and BOLD – fMRI signals
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2018.06.019
Abstract: BACKGROUND Depression is a heterogeneous disorder, but the exact neuronal mechanisms causing the disease have not yet been discovered. METHODS/MATERIALS We have established a chronic unpredictable mild stress (CUMS) mouse model to explore the blood… read more here.
Keywords: depression; bold activity; hippocampus prefrontal; prefrontal cortex ... See more keywords
Hippocampus and prefrontal cortex exhibit spindle-like waves during REM sleep
Sign Up to like & getrecommendations! Published in 2018 at "Neurophysiologie Clinique"
DOI: 10.1016/j.neucli.2018.05.021
Abstract: Objectives Spindles are considered as a major hallmark of non REM sleep (NREMS). These 10–16 Hz phasic oscillations are generated by thalamocortical loops. They are distributed in superficial and deep cortical structures, but also in the… read more here.
Keywords: rem sleep; hippocampus; spindle like; pfc ... See more keywords
Long-term potentiation prevents ketamine-induced aberrant neurophysiological dynamics in the hippocampus-prefrontal cortex pathway in vivo
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-63979-5
Abstract: N-methyl-D-aspartate receptor (NMDAr) antagonists such as ketamine (KET) produce psychotic-like behavior in both humans and animal models. NMDAr hypofunction affects normal oscillatory dynamics and synaptic plasticity in key brain regions related to schizophrenia, particularly in… read more here.
Keywords: long term; term potentiation; hippocampus prefrontal; prefrontal cortex ... See more keywords
Melatonin Attenuates Methotrexate-Induced Reduction of Antioxidant Activity Related to Decreases of Neurogenesis in Adult Rat Hippocampus and Prefrontal Cortex
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/1596362
Abstract: Previous studies have revealed that the side effects of anticancer drugs induce a decrease of neurogenesis. Methotrexate (MTX), one of anticancer drugs, can induce lipid peroxidation as an indicator of oxidative stress in the brain.… read more here.
Keywords: mtx; adult rat; hippocampus prefrontal; rat hippocampus ... See more keywords
Brain Region Specificity of Mitochondrial Biogenesis and Bioenergetics Response to Nrf2 Knockdown: A Comparison Among Hippocampus, Prefrontal Cortex and Amygdala of Male Rat Brain
Sign Up to like & getrecommendations! Published in 2017 at "Brazilian Archives of Biology and Technology"
DOI: 10.1590/1678-4324-2017160744
Abstract: Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) has been identified as the well-known coordinator of intracellular antioxidant defense system. Herein, we aimed to evaluate the effects of Nrf2 silencing on mitochondrial biogenesis markers peroxisome proliferator-activated receptor… read more here.
Keywords: mitochondrial biogenesis; brain; hippocampus prefrontal; prefrontal cortex ... See more keywords
Differential Regulation of DNA Methylation at the CRMP2 Promoter Region Between the Hippocampus and Prefrontal Cortex in a CUMS Depression Model
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2020.00141
Abstract: Current evidence supports the idea that neural plasticity is a potential cause of depression. Abundant studies indicate that CRMP2 has important roles in neural plasticity. Moreover, CRMP2 may contribute to the etiology of depression. However,… read more here.
Keywords: depression; crmp2; hippocampus prefrontal; dna methylation ... See more keywords
Chronic stress causes protein kinase C epsilon-aldehyde dehydrogenase 2 signaling pathway perturbation in the rat hippocampus and prefrontal cortex, but not in the myocardium
Sign Up to like & getrecommendations! Published in 2018 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.235060
Abstract: Chronic stress is strongly associated with the occurrence and development of depression and cardiovascular disease. Stress can induce altered mitochondrial function and activation of apoptosis in the cardio-cerebral system. However, it is unknown whether the… read more here.
Keywords: chronic stress; myocardium; hippocampus prefrontal; prefrontal cortex ... See more keywords