M97 TRANSCRIPTIONAL SIGNATURES OF CHILDHOOD ONSET SCHIZOPHRENIA IN HIPSC-DERIVED NPCS AND NEURONS ARE CONCORDANT WITH SIGNATURES FROM POST MORTEM ADULT BRAINS
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DOI: 10.1016/j.euroneuro.2017.08.404
Abstract: Background Large-scale Genome Wide Association Studies (GWAS) revealed that Schizophrenia (SZ) risk reflects both rare and common variants. Whereas highly penetrant rare variants have proven well-suited to human induced pluripotent stem cell (hiPSC)-based models, the… read more here.
Keywords: hipsc derived; hipsc; hipsc based; post mortem ... See more keywords