Human induced pluripotent stem cell-derived platelets loaded with lapatinib effectively target HER2+ breast cancer metastasis to the brain
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DOI: 10.1038/s41598-021-96351-2
Abstract: Prognosis of patients with HER2+ breast-to-brain-metastasis (BBM) is dismal even after current standard-of-care treatments, including surgical resection, whole-brain radiation, and systemic chemotherapy. Radiation and systemic chemotherapies can also induce cytotoxicity, leading to significant side effects. Studies… read more here.
Keywords: her2 breast; hipsc platelets; human induced; induced pluripotent ... See more keywords