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Endothelial Insulin Receptor Restoration Rescues Vascular Function in Male Insulin Receptor Haploinsufficient Mice

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Published in 2018 at "Endocrinology"

DOI: 10.1210/en.2018-00215

Abstract: Abstract Reduced systemic insulin signaling promotes endothelial dysfunction and diminished endogenous vascular repair. We investigated whether restoration of endothelial insulin receptor expression could rescue this phenotype. Insulin receptor knockout (IRKO) mice were crossed with mice… read more here.

Keywords: insulin; endothelial insulin; hireco; insulin receptor ... See more keywords