Hispidulin exerts a protective effect against oleic acid induced-ARDS in the rat via inhibition of ACE activity and MAPK pathway.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of environmental health research"
DOI: 10.1080/09603123.2023.2166023
Abstract: This study investigates the protective role of Hispidulin on acute respiratory distress syndrome (ARDS) in rats. Rats were divided into three groups: control, ARDS, ARDS+ Hispidulin. The ARDS models were established by injecting rats with oleic… read more here.
Keywords: ace; inhibition ace; protective effect; activity ... See more keywords
Flavonoids and the Subchronic Toxicity, Antipeptic Ulcer, and Analgesic Effects of the Ethyl Acetate Soluble Fraction of the Ethanol Extract from Sanchezia nobilis Hook. f Leaves
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DOI: 10.1177/1934578x221126306
Abstract: Seven known flavonoids were isolated from the ethyl acetate fraction of the 80% ethanol extract of Sanchezia nobilis Hook. f leaves (EASN). The 7 known compounds as hispidulin (4′,5,7-trihydroxy-6-methoxyflavone) (1), hispidulin-7-O-α-galactopyranoside (2), hispidulin-4′-O-β-galactopyranoside (3), hispidulin-7-O-β-galacturonide… read more here.
Keywords: fraction ethanol; ethanol extract; fraction; ethyl acetate ... See more keywords
Anti-Proliferative and Anti-Migratory Activities of Hispidulin on Human Melanoma A2058 Cells
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DOI: 10.3390/biom11071039
Abstract: Melanoma represents less than 5% of skin cancers, but is the most lethal, mainly because of its high-metastatic potential and resistance to various therapies. Therefore, it is important to develop effective treatments, especially chemotherapeutic drugs… read more here.
Keywords: melanoma; anti proliferative; hispidulin; a2058 cells ... See more keywords
Hispidulin Ameliorates Endotoxin-Induced Acute Kidney Injury in Mice
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27062019
Abstract: Lipopolysaccharide (LPS) is an endotoxin that plays a crucial role in septic acute kidney injury (AKI). Hispidulin is a natural flavonoid that possesses various biological activities. Recent studies have shown that hispidulin administration alleviates various… read more here.
Keywords: acute kidney; hispidulin; hispidulin administration; kidney injury ... See more keywords