Histidine substitution in the most flexible fragments of firefly luciferase modifies its thermal stability.
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DOI: 10.1016/j.abb.2017.07.003
Abstract: Molecular dynamics (MD) at two temperatures of 300 and 340 K identified two histidine residues, His461 and His489, in the most flexible regions of firefly luciferase, a light emitting enzyme. We therefore designed four protein mutants… read more here.
Keywords: temperature; firefly luciferase; histidine substitution; substitution ... See more keywords