Lewis fucose is a key moiety for the recognition of histo‐blood group antigens by GI.9 norovirus, as revealed by structural analysis
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DOI: 10.1002/2211-5463.13370
Abstract: Noroviruses have been identified as major causative agents of acute nonbacterial gastroenteritis in humans. Histo‐blood group antigens (HBGAs) are thought to play a major role among the host cellular factors influencing norovirus infection. Genogroup I,… read more here.
Keywords: histo blood; lewis fucose; group antigens; blood group ... See more keywords
Association between circulating rotavirus genotypes and histo‐blood group antigens in the children hospitalized with acute gastroenteritis in Iran
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medical Virology"
DOI: 10.1002/jmv.26808
Abstract: Rotaviruses are the dominant cause of severe acute gastroenteritis in children under 5 years of age. Previous studies showed that some children are less susceptible to rotavirus gastroenteritis. It has been shown that this resistance… read more here.
Keywords: group; histo blood; rotavirus; rotavirus gastroenteritis ... See more keywords
Association of histo‐blood group antigens and predisposition to gastrointestinal diseases
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DOI: 10.1002/jmv.28028
Abstract: Infectious gastroenteritis is a common illness afflicting people worldwide. The two most common etiological agents of viral gastroenteritis, rotavirus and norovirus are known to recognize histo‐blood group antigens (HBGAs) as attachment receptors. ABO, Lewis, and… read more here.
Keywords: predisposition; hbgas; histo blood; blood group ... See more keywords
ELISA-Based Methods to Detect and Quantify Norovirus Virus-Like Particle Attachment to Histo-Blood Group Antigens.
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DOI: 10.1007/978-1-0716-0430-4_51
Abstract: Histo-blood group antigen (HBGA) recognition by norovirus (NoV) has been studied using various techniques. Enzyme-linked immunosorbent assays (ELISAs) using virus-like particles (VLPs) have enabled us to visualize the last step of HBGAs-NoV binding with a… read more here.
Keywords: blood group; elisa based; virus like; histo blood ... See more keywords
Histo-blood group antigens in Crassostrea gigas and binding profiles with GII.4 Norovirus
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DOI: 10.1007/s00343-018-7024-x
Abstract: Noroviruses (NoVs) are the main cause of viral gastroenteritis outbreaks worldwide, and oysters are the most common carriers of NoV contamination and transmission. NoVs bind specifically to oyster tissues through histo-blood group antigens (HBGAs), and… read more here.
Keywords: hbgas; histo blood; bound type; binding ... See more keywords
Binding of rabbit hemorrhagic disease virus-like particles to host histo-blood group antigens is blocked by antisera from experimentally vaccinated rabbits
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Virology"
DOI: 10.1007/s00705-017-3509-8
Abstract: During infection host histo-blood group antigens (HBGAs) act as attachment factors that interact with rabbit hemorrhagic disease virus (RHDV) and participate in the infectious process. In the present study, baculovirus expressing recombinant RHDV capsid protein… read more here.
Keywords: host histo; rhdv; group; histo blood ... See more keywords
Histo-Blood Group Antigen Presentation Is Critical for Binding of Norovirus VLP to Glycosphingolipids in Model Membranes.
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DOI: 10.1021/acschembio.7b00152
Abstract: Virus entry depends on biomolecular recognition at the surface of cell membranes. In the case of glycolipid receptors, these events are expected to be influenced by how the glycan epitope close to the membrane is… read more here.
Keywords: chain; presentation; type chain; histo blood ... See more keywords
ABO, secretor, and Lewis carbohydrate histo‐blood groups are associated with autoimmune neutropenia of early childhood in Danish patients
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DOI: 10.1111/trf.17002
Abstract: Autoimmune neutropenia of early childhood (AIN) is caused by autoantibodies directed against antigens on the neutrophil membrane. The ABO, secretor, and Lewis histo‐blood group systems control the expression of carbohydrate antigens and have previously been… read more here.
Keywords: secretor lewis; early childhood; histo blood; neutropenia early ... See more keywords
Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies
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DOI: 10.1128/jvi.01833-22
Abstract: Human noroviruses are highly contagious and a major problem in closed institutions, such as schools, hospitals, and cruise ships. Reducing norovirus infections is challenging on multiple levels and includes the frequent emergence of antigenic variants,… read more here.
Keywords: hbga; nanobodies bound; norovirus; histo blood ... See more keywords
The Role of Histo-Blood Group Antigens and Microbiota in Human Norovirus Replication in Zebrafish Larvae
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DOI: 10.1128/spectrum.03157-22
Abstract: Despite causing over 700 million infections yearly, many gaps remain in the knowledge of human norovirus (HuNoV) biology due to an historical lack of efficient cultivation systems. Fucose-containing carbohydrate structures, named histo-blood group antigens, are… read more here.
Keywords: hunov; zebrafish larvae; replication; histo blood ... See more keywords
Infection of porcine small intestinal enteroids with human and pig rotavirus A strains reveals contrasting roles for histo-blood group antigens and terminal sialic acids
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DOI: 10.1371/journal.ppat.1009237
Abstract: Rotaviruses (RVs) are a leading cause of acute viral gastroenteritis in young children and livestock worldwide. Growing evidence suggests that host cellular glycans, such as histo-blood group antigens (HBGAs) and sialic acids (SA), are recognized… read more here.
Keywords: blood group; group antigens; sialic acids; histo blood ... See more keywords