Origin and evolution of the major histocompatibility complex class I region in eutherian mammals
Sign Up to like & getrecommendations! Published in 2019 at "Ecology and Evolution"
DOI: 10.1002/ece3.5373
Abstract: Abstract Major histocompatibility complex (MHC) genes in vertebrates are vital in defending against pathogenic infections. To gain new insights into the evolution of MHC Class I (MHCI) genes and test competing hypotheses on the origin… read more here.
Keywords: region; major histocompatibility; histocompatibility complex; class ... See more keywords
Multiple major histocompatibility complex class I genes in Asian anurans: Ontogeny and phylogeny
Sign Up to like & getrecommendations! Published in 2017 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2016.12.003
Abstract: ABSTRACT Amphibians, as the first terrestrial vertebrates, offer a window into early major histocompatibility complex (MHC) evolution. We characterized the MHC class I of two Korean amphibians, the Asiatic toad (Bufo gargarizans) and the Japanese… read more here.
Keywords: class; histocompatibility complex; major histocompatibility; mhc ... See more keywords
Characterisation of major histocompatibility complex class I transcripts in an Australian dragon lizard
Sign Up to like & getrecommendations! Published in 2018 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2018.02.012
Abstract: &NA; Characterisation of squamate major histocompatibility complex (MHC) genes has lagged behind other taxonomic groups. MHC genes encode cell‐surface glycoproteins that present self‐ and pathogen‐derived peptides to T cells and play a critical role in… read more here.
Keywords: class; histocompatibility complex; class transcripts; major histocompatibility ... See more keywords
More than skin deep: Major histocompatibility complex (MHC)-based attraction among Asian American speed-daters
Sign Up to like & getrecommendations! Published in 2018 at "Evolution and Human Behavior"
DOI: 10.1016/j.evolhumbehav.2018.04.001
Abstract: Abstract What might explain our instinctual attraction to certain individuals, aside from visible factors such as appearance? We examined possible biologically-driven selection for immunology genes, specifically preferences for Major Histocompatibility Complex (MHC)-dissimilarity, through the ecologically-valid… read more here.
Keywords: histocompatibility complex; complex mhc; mhc based; speed ... See more keywords
Identification of monoclonal antibodies cross-reactive with bottlenose dolphin orthologues of the major histocompatibility complex and leukocyte differentiation molecules.
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary immunology and immunopathology"
DOI: 10.1016/j.vetimm.2017.09.007
Abstract: The slow progress in understanding immunotoxic effects of environmental contaminants and their influence on disease susceptibility in whales is largely due to the limited information available on the immune systems and immune function of species… read more here.
Keywords: differentiation molecules; leukocyte differentiation; histocompatibility complex; cross reactive ... See more keywords
Adaptive selection signatures in river buffalo with emphasis on immune and major histocompatibility complex genes.
Sign Up to like & getrecommendations! Published in 2021 at "Genomics"
DOI: 10.1016/j.ygeno.2021.08.021
Abstract: River buffalo is an agriculturally important species with many traits, such as disease tolerance, which promote its use worldwide. Highly contiguous genome assemblies of the river buffalo, goat, pig, human and two cattle subspecies were… read more here.
Keywords: immune; river buffalo; histocompatibility complex; selection ... See more keywords
Destabilizing single chain major histocompatibility complex class I protein for repurposed enterokinase proteolysis
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-71785-2
Abstract: The lack of a high throughput assay for screening stabilizing peptides prior to building a library of peptide-major histocompatibility complex class I (pMHC-I) molecules has motivated the continual use of in silico tools without biophysical… read more here.
Keywords: protein; chain; histocompatibility complex; major histocompatibility ... See more keywords
Heterozygosity of the major histocompatibility complex predicts later self-reported pubertal maturation in men
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-99334-5
Abstract: Individual variation in the age of pubertal onset is linked to physical and mental health, yet the factors underlying this variation are poorly understood. Life history theory predicts that individuals at higher risk of mortality… read more here.
Keywords: reported pubertal; histocompatibility complex; heterozygosity major; major histocompatibility ... See more keywords
Partial peptide dissociation and binding groove plasticity in two major histocompatibility complex class I alleles – differences between alleles versus force field and sampling effects
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra05324a
Abstract: Major histocompatibility complex class I (MHC I) reports a cell's health status by presenting antigenic peptides inside its binding groove. However, MHC I binding grooves can differ largely in their plasticity, from binding grooves that… read more here.
Keywords: histocompatibility complex; dissociation; major histocompatibility; binding groove ... See more keywords
Major Histocompatibility Complex Class II in the red-tailed phascogale (Phascogale calura)
Sign Up to like & getrecommendations! Published in 2017 at "Australian Mammalogy"
DOI: 10.1071/am16002
Abstract: Diversity in major histocompatibility complex (MHC) genes can be correlated with the level of immunological fitness of an individual or group of individuals. This study tested published primer sets designed to amplify fragments of the… read more here.
Keywords: red tailed; class; histocompatibility complex; phascogale calura ... See more keywords
Inhibition of major histocompatibility complex-I antigen presentation by sarbecovirus ORF7a proteins
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2209042119
Abstract: Significance As part of the adaptive immune response, virus-infected cells present virus-derived peptides to cytotoxic T cells on the surface of infected cells, using a protein complex termed major histocompatibility complex class-I. Some viruses counteract… read more here.
Keywords: histocompatibility complex; orf7a proteins; antigen presentation; major histocompatibility ... See more keywords