Endoscopic remission assessed with PICaSSO virtual electronic chromendoscopy accurately predicts clinical outcomes in ulcerative colitis.
Sign Up to like & getrecommendations! Published in 2022 at "United European gastroenterology journal"
DOI: 10.1002/ueg2.12185
Abstract: BACKGROUND AND AIMS A composite endoscopic-histologic remission is increasingly explored as an important endpoint in ulcerative colitis (UC). We investigated combined endoscopic-histologic remission for predicting clinical outcomes at 12 months compared with endoscopic remission alone using… read more here.
Keywords: clinical outcomes; endoscopic remission; remission; histologic remission ... See more keywords
Intestinal barrier healing is superior to endoscopic and histologic remission for predicting major adverse outcomes in IBD: the prospective ERIca trial.
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology"
DOI: 10.1053/j.gastro.2022.10.014
Abstract: BACKGROUND Endoscopic and histologic remission have emerged as key therapeutic goals in the management of inflammatory bowel diseases (IBD) that are associated with favorable long-term disease outcomes. Here, we prospectively compared the predictive value of… read more here.
Keywords: endoscopic histologic; disease; barrier healing; remission ... See more keywords
P246 Histologic remission is an important therapeutic target in patients who achieve endoscopic remission of ulcerative colitis
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjad212.0376
Abstract: Histologic activity has been established as a crucial prognostic determinant in individuals diagnosed with ulcerative colitis(UC), while achieving histologic remission is increasingly recognized as a significant long-term therapeutic goal. However, the available literature still lacks… read more here.
Keywords: histologic remission; endoscopic remission; remission; ulcerative colitis ... See more keywords
P406 A novel active learning-based digital pathology protocol annotation for histologic assessment in Ulcerative Colitis using PICaSSO Histologic Remission Index (PHRI)
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DOI: 10.1093/ecco-jcc/jjad212.0536
Abstract: Histologic remission (HR) is a critical treatment target in Ulcerative Colitis (UC). Among several scoring systems, the PICaSSO Histologic Remission Index (PHRI) simplifies HR assessment by evaluating the presence of neutrophils in the bowel tissue.… read more here.
Keywords: histologic remission; pathology; annotation; colitis ... See more keywords
P0538 Histologic remission predicts relapse in patients with Ulcerative Colitis
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DOI: 10.1093/ecco-jcc/jjae190.0712
Abstract: Histologic remission is not currently established as a formal treatment target in ulcerative colitis (UC). However, growing evidence indicates that histologic activity is associated with increased rates of relapse, hospitalization, and colectomy1. We aimed to… read more here.
Keywords: clinical relapse; remission; ulcerative colitis; histologic remission ... See more keywords
Histologic Evaluation Using the Robarts Histopathology Index in Patients With Ulcerative Colitis in Deep Remission and the Association of Histologic Remission With Risk of Relapse.
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DOI: 10.1093/ibd/izab340
Abstract: BACKGROUND This study prospectively evaluated the risk of relapse according to the status of histologic activity in patients with ulcerative colitis (UC) who achieved deep remission. METHODS Patients with UC in clinical remission (partial Mayo… read more here.
Keywords: risk relapse; histopathology; remission; histologic remission ... See more keywords
Comparison of the Relative Sensitivity of Clinical, Endoscopic, and Histologic Remission for Detection of Treatment Efficacy in Ulcerative Colitis Trials.
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DOI: 10.1093/ibd/izac128
Abstract: This systemic review and quantitative analysis of placebo-controlled ulcerative colitis (UC) induction trials found higher pooled histologic remission rates compared with clinical and endoscopic remission rates at the same timepoint, and no significant differences in… read more here.
Keywords: ulcerative colitis; clinical endoscopic; remission; histologic remission ... See more keywords
Predictive accuracy of fecal calprotectin for histologic remission in ulcerative colitis
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DOI: 10.5217/ir.2024.00068
Abstract: Background/Aims Accurate assessment of disease activity is crucial for effective management and treatment of ulcerative colitis (UC). This study evaluated the correlation between clinical, endoscopic, and histologic measures of disease activity in UC. Methods Clinical,… read more here.
Keywords: endoscopic histologic; histologic remission; remission; accuracy ... See more keywords