Vemurafenib in patients with BRAFV600 mutant glioma: A cohort of the histology-independent VE-basket study.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.2004
Abstract: 2004Background: Recurrent malignant gliomas (MG) are a universally fatal disease in desperate need of better therapies. Pleiomorphic xanthoastrocytomas (PXA) and juvenile pilocytic astrocytomas (JPA) typically have better outcomes, although when recurrent, also represent an aggressive… read more here.
Keywords: independent basket; basket study; histology independent; histology ... See more keywords
Data Driven Kidney Transplant Phenotyping as a Histology-independent Framework for Biomarker Discovery.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2020121685
Abstract: BACKGROUND In transplant medicine, clinical decision-making largely relies on histology of biopsies. However, histology suffers from low specificity, sensitivity, and reproducibility, leading to suboptimal stratification of patients. We developed a histology-independent immune framework of kidney… read more here.
Keywords: kidney transplant; biomarker; histology independent; histology ... See more keywords