The first Entamoeba moshkovskii molecular detection in Egypt
Sign Up to like & getrecommendations! Published in 2018 at "Comparative Clinical Pathology"
DOI: 10.1007/s00580-018-2878-z
Abstract: Amebiasis infection is caused by Entamoeba histolytica. The nonpathogenic Entamoeba species, E. moshkovskii and E. dispar, are distinct but morphologically indifferentiable from E. histolytica, which led us to use of multiplex PCR to detect and… read more here.
Keywords: first entamoeba; moshkovskii; entamoeba species; egypt ... See more keywords
Characterization and validation of Entamoeba histolytica pantothenate kinase as a novel anti-amebic drug target
Sign Up to like & getrecommendations! Published in 2018 at "International Journal for Parasitology: Drugs and Drug Resistance"
DOI: 10.1016/j.ijpddr.2018.02.004
Abstract: The Coenzyme A (CoA), as a cofactor involved in >100 metabolic reactions, is essential to the basic biochemistry of life. Here, we investigated the CoA biosynthetic pathway of Entamoeba histolytica (E. histolytica), an enteric protozoan… read more here.
Keywords: pank; pantothenate kinase; kinase; novel anti ... See more keywords
Phosphorylation of Eukaryotic Initiation Factor 2-α in Response to Endoplasmic Reticulum and Nitrosative Stress in the human protozoan parasite, Entamoeba histolytica.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and biochemical parasitology"
DOI: 10.1016/j.molbiopara.2019.111223
Abstract: Entamoeba histolytica is an intestinal parasite infecting over 50 million people worldwide and is the causative agent of amebic dysentery and amoebic liver abscess. In the human host, E. histolytica experiences stress brought on by… read more here.
Keywords: response; stress; nitrosative stress; phosphorylation ... See more keywords
Linearolactone and Kaempferol Disrupt the Actin Cytoskeleton in Entamoeba histolytica: Inhibition of Amoebic Liver Abscess Development.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.0c00892
Abstract: Linearolactone (1) and kaempferol (2) have amebicidal activity in in vitro studies. The type of cell death induced by 1 and 2 and their effects on the virulence of E. histolytica were analyzed by transmission… read more here.
Keywords: actin cytoskeleton; linearolactone kaempferol; liver abscess; development ... See more keywords
Genetic, metabolomic and transcriptomic analyses of the de novo L-cysteine biosynthetic pathway in the enteric protozoan parasite Entamoeba histolytica
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-15923-3
Abstract: The de novo L-cysteine biosynthetic pathway is critical for the growth, antioxidative stress defenses, and pathogenesis of bacterial and protozoan pathogens, such as Salmonella typhimurium and Entamoeba histolytica. This pathway involves two key enzymes, serine… read more here.
Keywords: protozoan; cysteine biosynthetic; novo cysteine; entamoeba histolytica ... See more keywords
Pathogenicity and virulence of Entamoeba histolytica, the agent of amoebiasis
Sign Up to like & getrecommendations! Published in 2022 at "Virulence"
DOI: 10.1080/21505594.2022.2158656
Abstract: ABSTRACT The amoeba parasite Entamoeba histolytica is the causative agent of human amebiasis, an enteropathic disease affecting millions of people worldwide. This ancient protozoan is an elementary example of how parasites evolve with humans, e.g.… read more here.
Keywords: histolytica; agent; amoebiasis; virulence ... See more keywords
Multiplex PCR detection of Cryptosporidium sp, Giardia lamblia and Entamoeba histolytica directly from dried stool samples from Guinea-Bissauan children with diarrhoea
Sign Up to like & getrecommendations! Published in 2017 at "Infectious Diseases"
DOI: 10.1080/23744235.2017.1320728
Abstract: Abstract Background: In developing countries, diarrhoea is the most common cause of death for children under five years of age, with Giardia lamblia, Cryptosporidium and Entamoeba histolytica as the most frequent pathogenic parasites. Traditional microscopy… read more here.
Keywords: microscopy; cryptosporidium; giardia lamblia; entamoeba histolytica ... See more keywords
Iron responsive-like elements in the parasite Entamoeba histolytica.
Sign Up to like & getrecommendations! Published in 2017 at "Microbiology"
DOI: 10.1099/mic.0.000431
Abstract: In Entamoeba histolytica, iron modulates virulence and gene expression via unknown regulatory mechanisms. The existence of a posttranscriptional iron regulatory system parallel with the iron-responsive element (IRE)/iron regulatory protein (IRP) system in the protozoan Trichomonas… read more here.
Keywords: like elements; ire; iron responsive; entamoeba histolytica ... See more keywords
Entamoeba histolytica and Entamoeba dispar: Morphological and Behavioral Differences Induced by Fibronectin through GTPases Activation and Actin‐Binding Proteins
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Eukaryotic Microbiology"
DOI: 10.1111/jeu.12797
Abstract: Early steps of tissue invasion by Entamoeba histolytica are mediated by adhesion and migration through matrix components such as fibronectin with the participation of the actin cytoskeleton. Striking differences in their produced structures, movement, and… read more here.
Keywords: entamoeba histolytica; entamoeba dispar; activation; histolytica ... See more keywords
EhRho6‐mediated actin degradation in Entamoeba histolytica is associated with compromised pathogenicity
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Microbiology"
DOI: 10.1111/mmi.14896
Abstract: Entamoeba histolytica causes amoebiasis which is a major health concern in developing countries. E. histolytica pathogenicity has been implicated to a large repertoire of small GTPases which switch between the inactive GDP bound state and… read more here.
Keywords: entamoeba histolytica; actin degradation; pathogenicity; histolytica ... See more keywords
Trogocytosis by Entamoeba histolytica Mediates Acquisition and Display of Human Cell Membrane Proteins and Evasion of Lysis by Human Serum
Sign Up to like & getrecommendations! Published in 2019 at "mBio"
DOI: 10.1128/mbio.00068-19
Abstract: Entamoeba histolytica causes amoebiasis, a potentially fatal diarrheal disease. Abscesses in organs such as the liver can occur when amoebae are able to breach the intestinal wall and travel through the bloodstream to other areas… read more here.
Keywords: trogocytosis; histolytica; cell; cell membrane ... See more keywords