Articles with "histone binding" as a keyword



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Characterization of Caenorhabditis elegans Nucleosome Assembly Protein 1 Uncovers the Role of Acidic Tails in Histone Binding.

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Published in 2019 at "Biochemistry"

DOI: 10.1021/acs.biochem.8b01033

Abstract: Nucleosome assembly proteins (Naps) influence chromatin dynamics by directly binding to histones. Here we provide a comprehensive structural and biochemical analysis of a Nap protein from Caenorhabditis elegans (CeNap1). CeNap1 naturally lacks the acidic N-terminal… read more here.

Keywords: histone binding; uncovers role; h2a h2b; caenorhabditis elegans ... See more keywords
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Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release

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Published in 2017 at "Nature Communications"

DOI: 10.1038/s41467-017-02308-3

Abstract: Nucleoplasmin (Npm) is a highly conserved histone chaperone responsible for the maternal storage and zygotic release of histones H2A/H2B. Npm contains a pentameric N-terminal core domain and an intrinsically disordered C-terminal tail domain. Though intrinsically… read more here.

Keywords: tail domain; histone binding; histone; histone chaperone ... See more keywords
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Mapping of histone-binding sites in histone replacement-completed spermatozoa

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Published in 2018 at "Nature Communications"

DOI: 10.1038/s41467-018-06243-9

Abstract: The majority of histones are replaced by protamines during spermatogenesis, but small amounts are retained in mammalian spermatozoa. Since nucleosomes in spermatozoa influence epigenetic inheritance, it is important to know how histones are distributed in… read more here.

Keywords: replacement; histone binding; binding sites; histone replacement ... See more keywords
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ATRX histone binding and helicase activities have distinct roles in neuronal differentiation

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Published in 2022 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkac683

Abstract: Abstract ATRX is a chromatin remodeler, which is mutated in ATRX syndrome, a neurodevelopmental disorder. ATRX mutations that alter histone binding or chromatin remodeling activities cluster in the PHD finger or the helicase domain respectively.… read more here.

Keywords: histone; helicase; atrx histone; atrx mutations ... See more keywords
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A Variant of the Histone-Binding Protein sNASP Contributes to Mouse Lupus

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Published in 2019 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2019.00637

Abstract: The Sle2c1rec1c (rec1c) sublocus is derived from the mouse lupus susceptibility 2 (Sle2) locus identified in the NZM2410 model. Our current study dissected the functional characters and the genetic basis of the rec1c locus relative… read more here.

Keywords: histone binding; protein snasp; rec1c; mouse lupus ... See more keywords