Integrative Chemical Biology Approaches to Deciphering the Histone Code: A Problem-Driven Journey.
Sign Up to like & getrecommendations! Published in 2021 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.1c00463
Abstract: ConspectusThe hereditary blueprint of a eukaryotic cell is encoded in its genomic DNA that is tightly compacted into chromatin together with histone proteins. The basic repeating units of chromatin fibers are nucleosomes, in which approximately… read more here.
Keywords: histone ptms; histone code; histone; biology ... See more keywords
The histone code of the fungal genus Aspergillus uncovered by evolutionary and proteomic analyses
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Genomics"
DOI: 10.1099/mgen.0.000856
Abstract: Chemical modifications of DNA and histone proteins impact the organization of chromatin within the nucleus. Changes in these modifications, catalyzed by different chromatin-modifying enzymes, influence chromatin organization, which in turn is thought to impact the… read more here.
Keywords: chromatin modifications; histone code; chromatin; fungal genus ... See more keywords
Heterochromatin Protein 1: A Multiplayer in Cancer Progression
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DOI: 10.3390/cancers14030763
Abstract: Simple Summary Heterochromatin protein 1 is a histone code reader protein that recognizes histone H3 lysine 9 methylation. It acts as a transcriptional corepressor by forming heterochromatin. Since its discovery, the crucial roles of heterochromatin… read more here.
Keywords: cancer; heterochromatin; histone code; heterochromatin protein ... See more keywords