A histone H2A-derived antimicrobial peptide, Hipposin from mangrove whip ray, Himantura walga: Molecular and functional characterisation
Sign Up to like & getrecommendations! Published in 2020 at "3 Biotech"
DOI: 10.1007/s13205-020-02455-3
Abstract: Antimicrobial peptides (AMPs) are biologically dynamic molecules produced by all type of organisms as a fundamental component of their innate immune system. The present study deals with the identification of a histone H2A-derived antimicrobial peptide,… read more here.
Keywords: peptide; h2a derived; histone h2a; hipposin ... See more keywords
Maintenance of meiotic crossover against reduced double-strand break formation in fission yeast lacking histone H2A.Z.
Sign Up to like & getrecommendations! Published in 2020 at "Gene"
DOI: 10.1016/j.gene.2020.144615
Abstract: Meiotic crossover (CO) recombination initiates from programmed DNA double-strand breaks (DSBs) around hotspots, and results in reciprocal exchange of chromosome segments between homologous chromosomes (homologs). COs are crucial for most sexually-reproducing organisms because it promotes… read more here.
Keywords: formation; histone h2a; h2a; double strand ... See more keywords
Histone H2A Ubiquitination Reinforces Mechanical Stability and Asymmetry at Single-nucleosome Level.
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DOI: 10.1021/jacs.9b12448
Abstract: Mono-ubiquitination at Lysine 119 of H2A (ubH2A) is a prevalent post-translational modification and associated with gene repression in the context of chromatin. However, the direct function of ubH2A on nucleosome is poorly understood. Here we… read more here.
Keywords: histone h2a; asymmetry; h2a; ubh2a nucleosome ... See more keywords
Effects of charge-modifying mutations in histone H2A α3-domain on nucleosome stability assessed by single-pair FRET and MD simulations
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DOI: 10.1038/s41598-017-13416-x
Abstract: Nucleosomes are important for chromatin compaction and gene regulation; their integrity depends crucially on the structural properties of the histone tails. Recent all-atom molecular dynamics simulations revealed that removal of the N-terminal tails of histone… read more here.
Keywords: charge modifying; histone h2a; nucleosome stability; h2a ... See more keywords
Crosstalks between NOD1 and Histone H2A Contribute to Host Defense against Streptococcus agalactiae Infection in Zebrafish
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DOI: 10.3390/antibiotics10070861
Abstract: Correlation studies about NOD1 and histones have not been reported. In the present study, we report the functional correlation between NOD1 and the histone H2A variant in response to Streptococcus agalactiae infection. In zebrafish, NOD1… read more here.
Keywords: histone h2a; nod1 histone; histone; agalactiae infection ... See more keywords
Immunohistochemical Pattern of Histone H2A Variant Expression in an Experimental Model of Ischemia–Reperfusion-Induced Acute Kidney Injury
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24098085
Abstract: Ischemia–reperfusion injury (IRI) is a frequent cause of AKI, resulting in vasoconstriction, cellular dysfunction, inflammation and the induction of oxidative stress. DNA damage, including physical DNA strand breaks, is also a potential consequence of renal… read more here.
Keywords: histone h2a; ischemia reperfusion; histone; expression ... See more keywords
White Tea Intake Abrogates Markers of Streptozotocin-Induced Prediabetes Oxidative Stress in Rat Lungs’
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DOI: 10.3390/molecules26133894
Abstract: Prediabetes (PrDM) is a prodromal stage of diabetes mellitus (DM) with an increasing prevalence worldwide. During DM progression, individuals gradually develop complications in various organs. However, lungs are suggested to be affected later than other… read more here.
Keywords: intake abrogates; tea intake; histone h2a; white tea ... See more keywords