2,4-Dimethylaniline generates phosphorylated histone H2AX in human urothelial and hepatic cells through reactive oxygen species produced by cytochrome P450 2E1
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DOI: 10.1007/s00204-018-2289-6
Abstract: The Japanese Ministry of Health, Labour, and Welfare recently reported an outbreak of bladder cancer among workers who handled aromatic amines in Japan. 2,4-dimethylaniline (2,4-DMA) is one of the chemicals that workers are considered to… read more here.
Keywords: reactive oxygen; histone h2ax; oxygen species; h2ax ... See more keywords