Molecular interaction between human SUMO-I and histone like DNA binding protein of Helicobacter pylori (Hup) investigated by NMR and other biophysical tools.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.11.054
Abstract: The proteins secreted by bacteria contribute to immune mediated gastric inflammation and epithelial damage; thus aid bacterial invasion in host tissue, and may also interact with host proteins, conspirating a mechanism against host-immune system. The… read more here.
Keywords: hup; histone like; dna; binding protein ... See more keywords
Conserved Apical Proline Regulating the Structure and DNA Binding Properties of Helicobacter pylori Histone-like DNA Binding Protein (Hup)
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c01754
Abstract: Prokaryotic cells lack a proper dedicated nuclear arrangement machinery. A set of proteins known as nucleoid associated proteins (NAPs) perform opening and closure of nucleic acids, behest cellular requirement. Among these, a special class of… read more here.
Keywords: dna; structure; hup; dna binding ... See more keywords
Enhanced conformational flexibility of the histone-like (HU) protein from Mycoplasma gallisepticum
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2016.1264893
Abstract: The histone-like (HU) protein is one of the major nucleoid-associated proteins involved in DNA supercoiling and compaction into bacterial nucleoid as well as in all DNA-dependent transactions. This small positively charged dimeric protein binds DNA… read more here.
Keywords: protein; histone like; dna; like protein ... See more keywords
An archaeal histone-like protein regulates gene expression in response to salt stress
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab1175
Abstract: Abstract Histones, ubiquitous in eukaryotes as DNA-packing proteins, find their evolutionary origins in archaea. Unlike the characterized histone proteins of a number of methanogenic and themophilic archaea, previous research indicated that HpyA, the sole histone… read more here.
Keywords: histone like; histone; like protein; gene expression ... See more keywords
Posttranslational modification of a histone-like protein regulates phenotypic resistance to isoniazid in mycobacteria
Sign Up to like & getrecommendations! Published in 2018 at "Science Advances"
DOI: 10.1126/sciadv.aao1478
Abstract: A bacterial histone-like protein regulates the formation of privileged, drug-tolerant subpopulations of mycobacteria. There is increasing evidence that phenotypically drug-resistant bacteria may be important determinants of antibiotic treatment failure. Using high-throughput imaging, we defined distinct… read more here.
Keywords: protein; posttranslational modification; histone like; like protein ... See more keywords
Faster diffusive dynamics of histone-like nucleoid structuring proteins in live bacteria caused by silver ions.
Sign Up to like & getrecommendations! Published in 2020 at "Applied and environmental microbiology"
DOI: 10.1128/aem.02479-19
Abstract: The antimicrobial activity and mechanism of silver ions (Ag+) have gained broad attention in recent years. However, dynamic studies are rare in this field. Here, we report our measurement of the effects of Ag+ ions… read more here.
Keywords: silver ions; dynamics histone; histone like; microscopy ... See more keywords
Repression by the H-NS/YmoA histone-like protein complex enables IscR dependent regulation of the Yersinia T3SS
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1010321
Abstract: The type III secretion system (T3SS) is an appendage used by many bacterial pathogens, such as pathogenic Yersinia, to subvert host defenses. However, because the T3SS is energetically costly and immunogenic, it must be tightly… read more here.
Keywords: promoter; ymoa histone; repression; yersinia ... See more keywords
Phosphorylation Regulation of a Histone-like HU Protein from Deinococcus radiodurans
Sign Up to like & getrecommendations! Published in 2022 at "Protein and Peptide Letters"
DOI: 10.2174/0929866529666220819121911
Abstract: Background: Histone-like proteins are small molecular weight DNA-binding proteins that are widely distributed in prokaryotes. These proteins have multiple functions in cellular structures and processes, including the morphological stability of the nucleoid, DNA compactness, DNA… read more here.
Keywords: dna; like protein; histone like; phosphorylation ... See more keywords
Nε-Lysine Acetylation of the Histone-Like Protein HBsu Regulates the Process of Sporulation and Affects the Resistance Properties of Bacillus subtilis Spores
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.782815
Abstract: Bacillus subtilis produces dormant, highly resistant endospores in response to extreme environmental stresses or starvation. These spores are capable of persisting in harsh environments for many years, even decades, without essential nutrients. Part of the… read more here.
Keywords: acetylation; sporulation; hbsu; process sporulation ... See more keywords
Serotype conversion gene rfbT is directly regulated by histone-like nucleoid structuring protein (H-NS) in V. cholerae O1
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1111895
Abstract: Vibrio cholerae serogroup O1 (V. cholerae O1) is closely associated with cholera epidemics and has two main immunologically distinguishable serotypes, Ogawa and Inaba. Isolates serotype as Ogawa if the O-antigen polysaccharide (O-PS) is methylated or… read more here.
Keywords: nucleoid structuring; rfbt; cholerae; like nucleoid ... See more keywords