Dynamic changes in histone modification are associated with upregulation of Hsf and rRNA genes during heat stress in maize seedlings
Sign Up to like & getrecommendations! Published in 2019 at "Protoplasma"
DOI: 10.1007/s00709-019-01364-4
Abstract: Histone modification plays a significant role in plant responses to abiotic stress. However, there are little scientific studies available on the involvement of dynamic changes in histone modification in the heat stress response in maize.… read more here.
Keywords: histone modification; rrna; maize seedlings; heat stress ... See more keywords
Granulocyte Colony-Stimulating Factor Alleviates Bacterial-Induced Neuronal Apoptotic Damage in the Neonatal Rat Brain through Epigenetic Histone Modification
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/9797146
Abstract: Bacterial meningitis during the perinatal period may cause long-term neurological deficits. The study investigated whether bacterial lipopolysaccharide (LPS) derived from E. coli. led to neuronal apoptosis with an impaired performance of long-term cognitive function involving… read more here.
Keywords: histone modification; stimulating factor; colony stimulating; granulocyte colony ... See more keywords
Epi-miRNAs: Regulators of the Histone Modification Machinery in Human Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/4889807
Abstract: Cancer is a leading cause of death and disability worldwide. Epigenetic deregulation is one of the most critical mechanisms in carcinogenesis and can be classified into effects on DNA methylation and histone modification. MicroRNAs are… read more here.
Keywords: histone modification; modification machinery; cancer; modification ... See more keywords
Genetic Variants in Histone Modification Regions Predict Clinical Outcomes of Pemetrexed Chemotherapy in Lung Adenocarcinoma
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DOI: 10.1159/000527492
Abstract: Objective: This study was conducted to investigate the association between genetic variants in histone modification regions and clinical outcomes of PEM chemotherapy in patients with lung adenocarcinoma. Methods: Potentially functional SNPs were selected using integrated… read more here.
Keywords: variants histone; lung adenocarcinoma; genetic variants; histone modification ... See more keywords
Genome-wide identification of Gramineae histone modification genes and their potential roles in regulating wheat and maize growth and stress responses
Sign Up to like & getrecommendations! Published in 2021 at "BMC Plant Biology"
DOI: 10.1186/s12870-021-03332-8
Abstract: Background In plants, histone modification ( HM ) genes participate in various developmental and defense processes. Gramineae plants (e.g., Triticum aestivum , Hordeum vulgare , Sorghum bicolor , Setaria italica , Setaria viridis , and… read more here.
Keywords: histone modification; wheat; gramineae; stress ... See more keywords
Conservation and trans-regulation of histone modification in the A and B subgenomes of polyploid wheat during domestication and ploidy transition
Sign Up to like & getrecommendations! Published in 2021 at "BMC Biology"
DOI: 10.1186/s12915-021-00985-7
Abstract: Background Polyploidy has played a prominent role in the evolution of plants and many other eukaryotic lineages. However, how polyploid genomes adapt to the abrupt presence of two or more sets of chromosomes via genome… read more here.
Keywords: histone modification; wheat; ploidy; domestication ... See more keywords
Histone modification alteration coordinated with acquisition of promoter DNA methylation during Epstein-Barr virus infection
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19423
Abstract: Aberrant DNA hypermethylation is a major epigenetic mechanism to inactivate tumor suppressor genes in cancer. Epstein-Barr virus positive gastric cancer is the most frequently hypermethylated tumor among human malignancies. Herein, we performed comprehensive analysis of… read more here.
Keywords: histone modification; methylation; dna methylation; promoter ... See more keywords
Effects of histone modification in major depressive disorder.
Sign Up to like & getrecommendations! Published in 2021 at "Current neuropharmacology"
DOI: 10.2174/1570159x19666210922150043
Abstract: Major depressive disorder (MDD) is a disease associated with many factors; specifically, environmental, genetic, psychological, and biological factors play critical roles. Recent studies have demonstrated that histone modification may occur in the human brain in… read more here.
Keywords: depressive disorder; major depressive; histone modification; histone ... See more keywords
Histone Modification Landscapes as a Roadmap for Malaria Parasite Development
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.848797
Abstract: Plasmodium falciparum remains the deadliest parasite species in the world, responsible for 229 million cases of human malaria in 2019. The ability of the P. falciparum parasite to progress through multiple life cycle stages and… read more here.
Keywords: modification; histone; development; histone modification ... See more keywords
Perspectives on the Role of Histone Modification in Breast Cancer Progression and the Advanced Technological Tools to Study Epigenetic Determinants of Metastasis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2020.603552
Abstract: Metastasis is a complex process that involved in various genetic and epigenetic alterations during the progression of breast cancer. Recent evidences have indicated that the mutation in the genome sequence may not be the key… read more here.
Keywords: histone modification; breast cancer; metastasis; cancer ... See more keywords
Inflammation and histone modification in chronic pain
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1087648
Abstract: Increasing evidence suggests that epigenetic mechanisms have great potential in the field of pain. The changes and roles of epigenetics of the spinal cord and dorsal root ganglia in the chronic pain process may provide… read more here.
Keywords: histone modification; chronic pain; pain; inflammation histone ... See more keywords