The biological significance of histone modifiers in multiple myeloma: clinical applications
Sign Up to like & getrecommendations! Published in 2018 at "Blood Cancer Journal"
DOI: 10.1038/s41408-018-0119-y
Abstract: Multiple myeloma (MM) is a clonal plasma cell disorder that is characterized by a variety of genetic alterations. Recent studies have highlighted not only the importance of these genetic events but also epigenetic aberrations including… read more here.
Keywords: histone modifiers; multiple myeloma; clinical applications; histone ... See more keywords
Histone modifiers are oxygen sensors
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aaw8373
Abstract: Hypoxia signals directly to chromatin via histone demethylases to alter gene expression Approximately 2.6 billion years ago, during the Proterozoic period, the evolution of photosynthesis in cyanobacteria led to the introduction of the by-product of… read more here.
Keywords: oxygen; modifiers oxygen; histone modifiers; oxygen sensors ... See more keywords