Epigenetic histone modulations of PPARĪ³ and related pathways contribute to olanzapine-induced metabolic disorders.
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DOI: 10.1016/j.phrs.2020.104703
Abstract: The antipsychotic drug olanzapine is widely used in the treatment of schizophrenia, bipolar and other mental disorders; however, it causes serious metabolic disorders, including dyslipidemia. Our previous studies have identified that olanzapine activated expression of… read more here.
Keywords: olanzapine induced; epigenetic histone; metabolic disorders; histone ... See more keywords