Investigating the Histone Replacement Pathway in Sperm Using TPM
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DOI: 10.1016/j.bpj.2016.11.2013
Abstract: DNA is folded in drastically different ways in somatic cells and sperm cells. In somatic cells, DNA is wrapped around histone proteins and remains accessible for transcription and replication. However, in sperm cells, DNA is… read more here.
Keywords: replacement; investigating histone; histone replacement; replacement pathway ... See more keywords
Mapping of histone-binding sites in histone replacement-completed spermatozoa
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DOI: 10.1038/s41467-018-06243-9
Abstract: The majority of histones are replaced by protamines during spermatogenesis, but small amounts are retained in mammalian spermatozoa. Since nucleosomes in spermatozoa influence epigenetic inheritance, it is important to know how histones are distributed in… read more here.
Keywords: replacement; histone binding; binding sites; histone replacement ... See more keywords