The historical postulate: Is it the basis, at the level of the system, for self‐nonself discrimination?
Sign Up to like & getrecommendations! Published in 2021 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.13033
Abstract: Burnet envisaged the early presence of self‐antigens in development, or ‘the history’ of an animal, ablates the animal's ability to immunologically respond against them. Lederberg added the idea that the continuous presence of self‐antigens is… read more here.
Keywords: system; peripheral tolerance; historical postulate; activation ... See more keywords