Hit to Leads with Cytotoxic Effect in Leukemic Cells: Total Synthesis Intermediates as a Molecule Treasure Chest
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DOI: 10.1002/cmdc.202000066
Abstract: A previously designed and developed 12‐step total synthesis that includes [1,1′‐biphenyl]‐2‐amine and carbazole intermediates and that ultimately produces the carbazole alkaloid carbazomycin G was exploited as a screening compound library with the goal of identifying… read more here.
Keywords: total synthesis; leads cytotoxic; cytotoxic effect; hit leads ... See more keywords