Double‐hit lymphoma: So what?
Sign Up to like & getrecommendations! Published in 2019 at "Hematological Oncology"
DOI: 10.1002/hon.2581
Abstract: The revised WHO classification moved all aggressive B‐cell lymphomas with a MYC translocation and a concurrent translocation of BCL2 and/or BCL6 into a single diagnostic category. These are the double‐ and triple‐hit lymphomas. These represent… read more here.
Keywords: hit lymphoma; double hit; oncology; biology ... See more keywords
Current perspectives on the treatment of double hit lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Hematology"
DOI: 10.1080/17474086.2019.1623020
Abstract: ABSTRACT Introduction: Double hit lymphoma (DHL) represents a new diagnostic category with genetic, immunohistochemical and clinical characteristics intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma. Patients with DHL usually experience poor survival after frontline… read more here.
Keywords: lymphoma; double hit; treatment; hit lymphoma ... See more keywords
Poor outcomes for double‐hit lymphoma patients treated with curative‐intent second‐line immunochemotherapy following failure of intensive front‐line immunochemotherapy
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Haematology"
DOI: 10.1111/bjh.16319
Abstract: While patients with double‐hit lymphoma (DHL) are now frequently treated with intensive front‐line immunochemotherapy, outcomes for those who fail these regimens and subsequently receive curative‐intent second‐line immunochemotherapy are unknown. We identified 55 such patients who… read more here.
Keywords: double hit; line immunochemotherapy; line; hit lymphoma ... See more keywords
Dose‐adjusted EPOCH‐R is a safe and well tolerated outpatient treatment regimen in double‐hit lymphoma
Sign Up to like & getrecommendations! Published in 2022 at "Internal Medicine Journal"
DOI: 10.1111/imj.15747
Abstract: Double‐hit lymphoma (DHL) is an aggressive subtype of high‐grade B‐cell lymphoma with inferior prognosis using standard dose chemotherapy. Controversy remains whether more intensive chemotherapy regimens such as dose‐adjusted etoposide, prednisolone, vincristine, cyclophosphamide, doxorubicin and rituximab… read more here.
Keywords: hit lymphoma; double hit; dose adjusted; adjusted epoch ... See more keywords
Modified conditioning regimen with chidamide and high-dose rituximab for triple-hit lymphoma.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cellular and molecular medicine"
DOI: 10.1111/jcmm.16999
Abstract: Triple-hit lymphoma (THL), which is classified into high-grade B-cell lymphoma with rearrangements of MYC, BCL2 and BCL6, presents aggressive biological behaviour. High-dose chemotherapy followed by autologous hematopoietic stem cell transplantation (auto-HSCT) is considered to be… read more here.
Keywords: triple hit; dose rituximab; high dose; hit lymphoma ... See more keywords
Abstract 3831: Clinicopathologic determinants of survival in double/triple hit lymphoma: Analysis of a pooled database
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-3831
Abstract: Background B-cell lymphoma with MYC, BCL2, and/or BCL6 rearrangements are classified as double/triple- hit lymphoma (DTHL). They usually, but not always, tend to be high-grade aggressive B-cell lymphoma with worse prognosis. Despite this classification, DTHL… read more here.
Keywords: double triple; hit lymphoma; pooled database; triple hit ... See more keywords
How I treat double-hit lymphoma.
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood-2017-04-737320
Abstract: The 2016 revision of the World Health Organization (WHO) classification for lymphoma has included a new category of lymphoma, separate from diffuse large B-cell lymphoma, termed high-grade B-cell lymphoma with translocations involving myc and bcl-2… read more here.
Keywords: lymphoma; double hit; hit lymphoma; hit lymphomas ... See more keywords
Primary Cardiac Triple-Hit Lymphoma.
Sign Up to like & getrecommendations! Published in 2022 at "International heart journal"
DOI: 10.1536/ihj.21-513
Abstract: Cardiac double-hit and triple-hit lymphomas (DHLs, THLs) are rare; in fact, studies examining both DHL and THL remain scarce. THL with cardiac involvement constitutes a rare disease with few cases reported so far. Thus, in… read more here.
Keywords: triple hit; hit lymphoma; cardiac triple; primary cardiac ... See more keywords
Advancing the management of double hit lymphoma
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.20794
Abstract: Double hit lymphoma (DHL), commonly defined as an aggressive B cell non-Hodgkin lymphoma (NHL) harboring rearrangement of MYC as well as BCL2 and/or BCL6, has recently been formally categorized as “High grade B-cell lymphoma [HGBL],… read more here.
Keywords: lymphoma; double hit; dhl; hit lymphoma ... See more keywords