Double Arylation of the Indole Side Chain of Tri- and Tetrapodal Tryptophan Derivatives Renders Highly Potent HIV-1 and EV-A71 Entry Inhibitors
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DOI: 10.1021/acs.jmedchem.1c00315
Abstract: We have recently described a new generation of potent human immunodeficiency virus (HIV) and EV-A71 entry inhibitors. The prototypes contain three or four tryptophan (Trp) residues bearing an isophthalic acid moiety at the C2 position… read more here.
Keywords: entry inhibitors; a71 entry; hiv; side chain ... See more keywords