HIV Tat causes synapse loss in a mouse model of HIV‐associated neurocognitive disorder that is independent of the classical complement cascade component C1q
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DOI: 10.1002/glia.23511
Abstract: Microglial activation, increased proinflammatory cytokine production, and a reduction in synaptic density are key pathological features associated with HIV‐associated neurocognitive disorders (HAND). Even with combination antiretroviral therapy (cART), more than 50% of HIV‐positive individuals experience… read more here.
Keywords: hiv; complement; associated neurocognitive; tat ... See more keywords
MRI Assessment of Treatment Response in HIV‐associated NAFLD: A Randomized Trial of a Stearoyl‐Coenzyme‐A‐Desaturase‐1 Inhibitor (ARRIVE Trial)
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DOI: 10.1002/hep.30674
Abstract: Aramchol, an oral stearoyl‐coenzyme‐A‐desaturase‐1 inhibitor, has been shown to reduce hepatic fat content in patients with primary nonalcoholic fatty liver disease (NAFLD); however, its effect in patients with human immunodeficiency virus (HIV)–associated NAFLD is unknown.… read more here.
Keywords: trial; treatment; mri; associated nafld ... See more keywords
HIV‐associated thrombotic thrombocytopaenic purpura: A retrospective cohort study during the anti‐retroviral therapy era
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.21692
Abstract: HIV‐associated thrombotic thrombocytopaenic purpura (TTP) is thought to represent the majority of current TTP diagnoses in South Africa (SA). read more here.
Keywords: associated thrombotic; thrombocytopaenic purpura; hiv associated; thrombotic thrombocytopaenic ... See more keywords
Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders.
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DOI: 10.1007/7854_2019_123
Abstract: Evidence from epidemiological studies on the general population suggests that midlife cardiovascular disease (CVD) and/or metabolic syndrome (MetS) are associated with an increased risk of cognitive impairment and dementia later in life. In the modern… read more here.
Keywords: hiv; disease; metabolic syndrome; cardiovascular disease ... See more keywords
The Impact of HIV-Associated Neurocognitive Impairment on Driving Performance in Commercial Truck Drivers
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DOI: 10.1007/s10461-020-03033-7
Abstract: Driving ability can be diminished amongst people with HIV with associated neurocognitive impairment (NCI). We explore the relationship between HIV status, NCI and driving ability in professional truck drivers. Forty male professional drivers (20 HIV-positive;… read more here.
Keywords: neurocognitive impairment; associated neurocognitive; truck drivers; hiv associated ... See more keywords
HIV-Associated Neurocognitive Impairment Knowledge and Current Practices: A Survey of Frontline Healthcare Workers in South Africa
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DOI: 10.1007/s10900-020-00895-9
Abstract: Neurocognitive impairment (NCI) associated with the human immunodeficiency virus (HIV) remains prevalent amongst people living with HIV. Testing for HIV-associated NCI in routine clinical care is limited in South Africa and reasons for this are… read more here.
Keywords: south africa; knowledge; hiv; associated nci ... See more keywords
Childhood maltreatment and HIV-associated neurocognitive disorders share similar pathophysiology: a potential sensitisation mechanism?
Sign Up to like & getrecommendations! Published in 2017 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-017-0062-9
Abstract: AbstractHIV-associated neurocognitive disorders (HAND) are increasingly prevalent despite the use of antiretroviral therapies. Previous research suggests that individual host factors play an important role in determining susceptibility to HAND. In this review, we propose that… read more here.
Keywords: share; childhood; hand; neurocognitive disorders ... See more keywords
Monitoring HIV-Associated Neurocognitive Disorder Using Screenings: a Critical Review Including Guidelines for Clinical and Research Use
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DOI: 10.1007/s11904-017-0349-9
Abstract: Screening tools to identify HIV-associated neurocognitive disorder (HAND) are primarily devised to detect cognitive impairment on a single occasion. With the chronicity of HIV infection and the risk of HAND developing or progressing despite viral… read more here.
Keywords: use; screening tools; neurocognitive disorder; hand ... See more keywords
Update of HIV-Associated Sensory Neuropathies
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DOI: 10.1007/s11940-017-0472-3
Abstract: Purpose of reviewHIV-sensory neuropathy (HIV-SN) remains a common complication of HIV infection and may be associated with significant morbidity due to neuropathic pain. The overall purpose of this review is to discuss trends in the… read more here.
Keywords: hiv; update hiv; pain; associated sensory ... See more keywords
A mouse model of HIV-associated neurocognitive disorders: a brain-behavior approach to discover disease mechanisms and novel treatments
Sign Up to like & getrecommendations! Published in 2017 at "Journal of NeuroVirology"
DOI: 10.1007/s13365-017-0572-6
Abstract: HIV-associated neurocognitive disorders (HAND) remain highly prevalent despite combined antiretroviral therapy (cART). Although the most common forms of HAND are mild and identified through neuropsychological testing, there is evidence that with aging these mild forms… read more here.
Keywords: hiv; hand; model; neurocognitive disorders ... See more keywords
Association of age and time of disease with HIV-associated neurocognitive disorders: a Japanese nationwide multicenter study
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DOI: 10.1007/s13365-017-0580-6
Abstract: There is no detailed information on the association between age, time of disease, and HIV-associated neurocognitive disorders (HAND). In this prospective study involving 17 medical facilities across Japan, we recruited HIV-infected patients to complete a… read more here.
Keywords: age time; association age; age; hiv ... See more keywords