Optimization and qualification of a functional anti-drug antibody assay for HIV-1 bnAbs
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Immunological Methods"
DOI: 10.1016/j.jim.2020.112736
Abstract: The recent identification of human monoclonal antibodies with broad and potent neutralizing activity against HIV-1 (bnAbs) has resulted in substantial efforts to develop these molecules for clinical use in the prevention and treatment of HIV-1… read more here.
Keywords: antibody; anti drug; hiv; hiv bnabs ... See more keywords
[The affinity maturation, characteristics and application of HIV-1 broadly neutralizing antibodies].
Sign Up to like & getrecommendations! Published in 2022 at "Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]"
DOI: 10.3760/cma.j.cn112150-20210623-00606
Abstract: Hundreds of broadly neutralizing antibodies(bNAbs) were successfully isolated from long-term nonprogression(LTNP) of human immunodeficiency virus type 1(HIV-1) infected individuals. Some bNAbs were illustrated could reduce the viral load and the risk of HIV-1 infection. Today,… read more here.
Keywords: hiv bnabs; affinity maturation; affinity; neutralizing antibodies ... See more keywords