Phenotypically resembling myeloid derived suppressor cells are increased in children with HIV and exposed/infected with Mycobacterium tuberculosis
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Immunology"
DOI: 10.1002/eji.201646658
Abstract: Increased disease susceptibility during early life has been linked to immune immaturity, regulatory T‐cell/TH2 immune biasing and hyporesponsiveness. The contribution of myeloid derived suppressor cells (MDSCs) remains uninvestigated. Here, we assessed peripheral MDSC in HIV‐infected… read more here.
Keywords: suppressor cells; derived suppressor; hiv; hiv exposed ... See more keywords
Early child development in children who are HIV‐exposed uninfected compared to children who are HIV‐unexposed: observational sub‐study of a cluster‐randomized trial in rural Zimbabwe
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the International AIDS Society"
DOI: 10.1002/jia2.25456
Abstract: Exposure to maternal HIV may affect early child development (ECD), although previous studies have reported heterogeneous findings. We evaluated ECD among children who were HIV‐exposed uninfected (CHEU) and children who were HIV‐unexposed (CHU) recruited to… read more here.
Keywords: early child; exposed uninfected; children hiv; hiv unexposed ... See more keywords
Myocardial peak systolic velocity—a tool for cardiac screening of HIV-exposed uninfected children
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pediatrics"
DOI: 10.1007/s00431-019-03477-7
Abstract: HIV-uninfected children exposed prenatally to the virus and to prophylactic antiretroviral therapy are at an uncertain risk of long-term myocardial dysfunction. This study aimed to analyse the structure and function of their ventricles and to… read more here.
Keywords: peak systolic; uninfected children; exposed uninfected; myocardial peak ... See more keywords
Growth and Neurodevelopment of HIV-Exposed Uninfected Children: a Conceptual Framework
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DOI: 10.1007/s11904-019-00459-0
Abstract: The population of HIV-exposed uninfected (HEU) children is expanding rapidly, and over one million HEU infants are born each year globally. Several recent studies have reported that HEU children, particularly in low- and middle-income countries,… read more here.
Keywords: exposed uninfected; heu children; growth neurodevelopment; hiv exposed ... See more keywords
Neurodevelopment of HIV-exposed uninfected children compared with HIV-unexposed uninfected children during early childhood.
Sign Up to like & getrecommendations! Published in 2022 at "Developmental psychology"
DOI: 10.1037/dev0001319
Abstract: HIV-exposed uninfected (HEU) children during the preschool and early school ages may be at-risk for neurodevelopmental challenges due to in utero and perinatal exposure to HIV and/or antiretroviral (ARV) medications. HEU children and HIV-unexposed uninfected… read more here.
Keywords: age; heu children; hiv exposed; uninfected children ... See more keywords
Blood lead levels and neurodevelopmental function in perinatally HIV-exposed, uninfected children in a US-based longitudinal cohort study.
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DOI: 10.1089/aid.2016.0265
Abstract: BACKGROUND While children's exposure to environmental lead in the U.S. has decreased, areas of elevated levels remain. Because lead exposure is a risk factor for developmental delays, it should be considered when studying neurodevelopmental effects… read more here.
Keywords: uninfected children; elevated bpb; exposed uninfected; hiv exposed ... See more keywords
Factors Associated with Lower Respiratory Tract Infections in HIV-Exposed Uninfected Infants.
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DOI: 10.1089/aid.2017.0245
Abstract: To identify factors that predispose human immunodeficiency virus (HIV)-exposed uninfected infants (HEUs) to higher incidence of severe infections, hospitalization, and death in the first 6-24 months of life compared with HEUs with and without lower… read more here.
Keywords: lower respiratory; uninfected infants; exposed uninfected; lrti ... See more keywords
Rates and Predictors of HIV-Exposed Infants Lost to Follow-Up During Early Infant Diagnosis Services in Kenya.
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DOI: 10.1089/apc.2019.0050
Abstract: Early infant diagnosis (EID) involves age-specific tracking and testing of HIV-exposed infants during the first 18 months of life and rapid initiation of life-saving treatment for those infected. In Kenya, pre-2013 data estimate EID lost… read more here.
Keywords: early infant; eid; infant diagnosis; rates predictors ... See more keywords
In Utero Antiretroviral Exposure and Risk of Neurodevelopmental Problems in HIV-Exposed Uninfected 5-Year-Old Children.
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DOI: 10.1089/apc.2022.0189
Abstract: Studies have observed neurodevelopmental (ND) challenges among young children perinatally HIV-exposed yet uninfected (CHEU) with in utero antiretroviral (ARV) exposure, without clear linkage to specific ARVs. Atazanavir (ATV) boosted with ritonavir has been a preferred… read more here.
Keywords: risk signals; year old; risk; utero antiretroviral ... See more keywords
Follow-up and Clinical Outcomes of Human Immunodeficiency Virus (HIV)-Exposed Infants in A Low-Prevalence Setting in A Multidisciplinary Model of Care in Australia: The Children's HIV Exposure Study 1.
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DOI: 10.1093/jpids/piaa010
Abstract: BACKGROUND Prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) is effective, but outcome information beyond the postnatal period in low-prevalence settings is scarce. A multidisciplinary model of care (MOC) was developed to ensure… read more here.
Keywords: human immunodeficiency; low prevalence; virus hiv; immunodeficiency virus ... See more keywords
Human metapneumovirus-associated hospitalization in HIV-1 exposed uninfected and HIV-1 uninfected children less than 5 years in South Africa.
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DOI: 10.1093/jpids/piac112
Abstract: Using hospital surveillance data, we estimated hMPV hospitalization incidence by age and HIV-exposure status. hMPV-associated hospitalization incidence was highest in read more here.
Keywords: month children; hiv; associated hospitalization; children month ... See more keywords