Association of Endothelial Dysfunction and Antiretroviral Therapy in Early HIV Infection
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2019.13615
Abstract: Key Points Question Is endothelial dysfunction present in early HIV infection, and is reversal of endothelial dysfunction associated with antiretroviral therapy? Findings In this cohort study of 61 patients with early seroconversion to HIV infection… read more here.
Keywords: antiretroviral therapy; hiv infection; dysfunction; endothelial dysfunction ... See more keywords
Comparison of Overall and Comorbidity-Free Life Expectancy Between Insured Adults With and Without HIV Infection, 2000-2016.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2020.7954
Abstract: Importance Antiretroviral therapy (ART) has improved life expectancy for individuals with HIV infection, but recent data comparing life span and comorbidity-free years by HIV status are lacking. Objective To quantify the gap in life span… read more here.
Keywords: hiv infection; infection; individuals hiv; life expectancy ... See more keywords
Semen exosomes inhibit HIV infection and HIV‐induced proinflammatory cytokine production independent of the activation state of primary lymphocytes
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13653
Abstract: Semen exosomes (SE) inhibit HIV infection. However, the effect of SE on cell activation and inflammation remains unknown. We characterized the response of peripheral blood mononuclear cells (PBMCs) from HIV‐uninfected and antiretroviral therapy‐suppressed HIV‐infected (HIV+)… read more here.
Keywords: hiv infection; semen exosomes; exosomes inhibit; hiv ... See more keywords
Who is Advocating for Children and Adolescents With HIV Infection?
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DOI: 10.1002/cad.20344
Abstract: Despite significant gains in the past 10 years in the treatment and care of children and adolescents with HIV infection, there is still need for advocacy for this group. The author discusses how far we… read more here.
Keywords: adolescents hiv; hiv infection; advocating children; children adolescents ... See more keywords
Tearing down the false walls to HIV cancer care
Sign Up to like & getrecommendations! Published in 2019 at "Cancer"
DOI: 10.1002/cncr.31974
Abstract: In this issue of Cancer, Grover and colleagues report that, for women in Botswana with cervical cancer, curative-intent therapy with equivalent cisplatin-based radiochemotherapy is initiated independent of human immunodeficiency virus (HIV) serostatus. The investigators’ findings… read more here.
Keywords: cancer care; hiv infection; hiv; cervical cancer ... See more keywords
Abortive HIV‐1 RNA induces pro‐IL‐1β maturation via protein kinase PKR and inflammasome activation in humans
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Immunology"
DOI: 10.1002/eji.202149275
Abstract: The proinflammatory cytokine IL‐1β mediates high levels of immune activation observed during acute and chronic human immunodeficiency virus 1 (HIV‐1) infection. Little is known about the mechanisms that drive IL‐1β activation during HIV‐1 infection. Here,… read more here.
Keywords: hiv infection; hiv; activation; protein kinase ... See more keywords
Impact of HIV infection on Survival among Women with Stage I-III Breast Cancer: Results from the South African Breast Cancer and HIV Outcomes Study.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of cancer"
DOI: 10.1002/ijc.33981
Abstract: In some countries of sub-Saharan Africa, the prevalence of HIV exceeds 20%; in South Africa, 20.4% of people are living with HIV. We examined the impact of HIV infection on the overall survival (OS) of… read more here.
Keywords: cancer; breast cancer; hiv; hiv infection ... See more keywords
Evaluation of characteristic metabolites of aromatic amino acids in patients with HIV infection at different stages of disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24795
Abstract: Acquired immune deficiency syndrome (AIDS), human immunodeficiency virus (HIV) infection, and antiretroviral therapy are usually associated with metabolic disorders. Screening for biomarkers to evaluate the progression of metabolic disorders is important for the diagnosis and… read more here.
Keywords: infection; patients hiv; aromatic amino; evaluation characteristic ... See more keywords
The cost‐effectiveness and budgetary impact of a dolutegravir‐based regimen as first‐line treatment of HIV infection in India
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the International AIDS Society"
DOI: 10.1002/jia2.25085
Abstract: Dolutegravir (DTG)‐based antiretroviral therapy (ART) is recommended for first‐line HIV treatment in the US and Europe. Efavirenz (EFV)‐based regimens remain the standard of care (SOC) in India. We examined the clinical and economic impact of… read more here.
Keywords: hiv infection; dolutegravir; line; first line ... See more keywords
ART adherence and viral suppression are high among most non‐pregnant individuals with early‐stage, asymptomatic HIV infection: an observational study from Uganda and South Africa
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the International AIDS Society"
DOI: 10.1002/jia2.25232
Abstract: The success of universal antiretroviral therapy (ART) access and aspirations for an AIDS‐free generation depend on high adherence in individuals initiating ART during early‐stage HIV infection; however, adherence may be difficult in the absence of… read more here.
Keywords: hiv infection; early stage; art; adherence ... See more keywords
Liver function test abnormalities in a longitudinal cohort of Thai individuals treated since acute HIV infection
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the International AIDS Society"
DOI: 10.1002/jia2.25444
Abstract: Liver disease is a common cause of non‐AIDS morbidity and mortality in people living with HIV (PLHIV), but the prevalence and significance of liver function test (LFT) abnormalities in early HIV infection is unknown. This… read more here.
Keywords: hiv infection; liver function; function test; infection ... See more keywords