CD4+ T Cells Are Dispensable for Induction of Broad Heterologous HIV Neutralizing Antibodies in Rhesus Macaques
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.757811
Abstract: Induction of broadly neutralizing antibodies (bNAbs) is a major goal for HIV vaccine development. HIV envelope glycoprotein (Env)-specific bNAbs isolated from HIV-infected individuals exhibit substantial somatic hypermutation and correlate with T follicular helper (Tfh) responses.… read more here.
Keywords: hiv; neutralizing antibodies; heterologous hiv; rhesus macaques ... See more keywords
Nanoparticle Vaccines for Inducing HIV-1 Neutralizing Antibodies
Sign Up to like & getrecommendations! Published in 2019 at "Vaccines"
DOI: 10.3390/vaccines7030076
Abstract: The enormous sequence diversity between human immunodeficiency virus type 1 (HIV-1) strains poses a major roadblock for generating a broadly protective vaccine. Many experimental HIV-1 vaccine efforts are therefore aimed at eliciting broadly neutralizing antibodies… read more here.
Keywords: inducing hiv; hiv; neutralizing antibodies; hiv neutralizing ... See more keywords