Articles with "hiv pathogenesis" as a keyword



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HIV Pathogenesis in the Human Female Reproductive Tract

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Published in 2021 at "Current HIV/AIDS Reports"

DOI: 10.1007/s11904-021-00546-1

Abstract: Purpose of Review Women remain disproportionately affected by the HIV/AIDS pandemic. The primary mechanism for HIV acquisition in women is sexual transmission, yet the immunobiological factors that contribute to HIV susceptibility remain poorly characterized. Here,… read more here.

Keywords: hiv pathogenesis; hiv; pathogenesis; female reproductive ... See more keywords

Of mice, or men: TLR4 signaling in HIV pathogenesis.

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Published in 2023 at "Journal of leukocyte biology"

DOI: 10.1093/jleuko/qiad017

Abstract: A murine Tlr4null humanized mouse model offers a new tool to study mechanisms by which microbial translocation affects adaptive immune function and exacerbates HIV-1 pathogenesis. read more here.

Keywords: hiv pathogenesis; signaling hiv; tlr4 signaling; mice men ... See more keywords

Neutrophils in HIV pathogenesis: dual roles, clinical implications, and therapeutic frontiers

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Published in 2025 at "Annals of Medicine and Surgery"

DOI: 10.1097/ms9.0000000000003474

Abstract: Neutrophils, the most abundant innate immune cells, play a complex role in human immunodeficiency virus (HIV) infection, balancing between protective immunity and pathogenic inflammation. Initially, neutrophils contribute to early viral containment through phagocytosis, reactive oxygen… read more here.

Keywords: hiv pathogenesis; hiv; inflammation; neutrophils hiv ... See more keywords
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MiRNA expression profiling in HIV pathogenesis, disease progression and response to treatment: a systematic review.

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Published in 2021 at "Epigenomics"

DOI: 10.2217/epi-2021-0237

Abstract: Aim: A systematic review was conducted to identify the association of miRNA expression with HIV pathogenesis, progression and treatment. Methods: A search of articles was conducted in MEDLINE®, Cochrane Central Register of Controlled Trials and Global… read more here.

Keywords: hiv pathogenesis; systematic review; expression; progression ... See more keywords

The diverse roles of miRNAs in HIV pathogenesis: Current understanding and future perspectives

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1091543

Abstract: Despite noteworthy progress made in the management and treatment of HIV/AIDS-related disease, including the introduction of the now almost ubiquitous HAART, there remains much to understand with respect to HIV infection. Although some roles that… read more here.

Keywords: hiv pathogenesis; infection; roles mirnas; future perspectives ... See more keywords

Exosomes at the crossroads of HIV-1 pathogenesis and therapeutics

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Published in 2025 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2025.1634726

Abstract: Despite advances in antiretroviral therapy (ART), human immunodeficiency virus type 1 (HIV-1) remains a global health challenge, with approximately 39 million people infected worldwide, persistent viral reservoirs, and delayed immune reconstitution. Exosomes, which are extracellular… read more here.

Keywords: hiv pathogenesis; crossroads hiv; pathogenesis therapeutics; exosomes crossroads ... See more keywords

Applications of the FIV Model to Study HIV Pathogenesis

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Published in 2018 at "Viruses"

DOI: 10.3390/v10040206

Abstract: Feline immunodeficiency virus (FIV) is a naturally-occurring retrovirus that infects domestic and non-domestic feline species, producing progressive immune depletion that results in an acquired immunodeficiency syndrome (AIDS). Much has been learned about FIV since it… read more here.

Keywords: hiv pathogenesis; model; fiv; model study ... See more keywords

Host Molecule Incorporation into HIV Virions, Potential Influences in HIV Pathogenesis

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Published in 2022 at "Viruses"

DOI: 10.3390/v14112523

Abstract: During the last phase of HIV viral production, nascent HIV virions acquire a fraction of the cellular lipid membrane to create the external lipid envelope, a process by which cellular proteins present on the surface… read more here.

Keywords: hiv virions; hiv pathogenesis; hiv; host molecule ... See more keywords

Adaptor Protein Complexes in HIV-1 Pathogenesis: Mechanisms and Therapeutic Potential

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Published in 2025 at "Viruses"

DOI: 10.3390/v17050715

Abstract: Adaptor protein (AP) complexes are critical components of the cellular membrane transport machinery. They mediate cargo selection during endocytosis and intracellular vesicular trafficking. Five AP complexes have been characterized (AP1-5), and together their roles extend… read more here.

Keywords: pathogenesis mechanisms; hiv pathogenesis; adaptor protein; complexes hiv ... See more keywords