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   Articles with "hiv resistance" as a keyword



HIResist: a database of HIV-1 resistance to broadly neutralizing antibodies

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recommendations! Published in 2024 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btae103

Abstract: Abstract Motivation Changing the course of the human immunodeficiency virus type I (HIV-1) pandemic is a high public health priority with approximately 39 million people currently living with HIV-1 (PLWH) and about 1.5 million new… read more here.

Keywords: database; resistance; hiv; broadly neutralizing ... See more keywords

Identifying the HIV-Resistance-Related Factors and Regulatory Network via Multi-Omics Analyses

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recommendations! Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms252111757

Abstract: For research on HIV/AIDS, it is important to elucidate the complex viral–host interaction, host dependency factors (HDFs), and restriction factors. However, the regulatory network of HIV-resistance-related factors remains not well understood. Therefore, we integrated four… read more here.

Keywords: resistance; related factors; resistance related; hiv resistance ... See more keywords
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A Computational Approach for the Prediction of HIV Resistance Based on Amino Acid and Nucleotide Descriptors

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recommendations! Published in 2018 at "Molecules"

DOI: 10.3390/molecules23112751

Abstract: The high variability of the human immunodeficiency virus (HIV) is an important cause of HIV resistance to reverse transcriptase and protease inhibitors. There are many variants of HIV type 1 (HIV-1) that can be used… read more here.

Keywords: hiv resistance; prediction; resistance; amino acid ... See more keywords

Decoding HIV resistance: from genotype to therapy.

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recommendations! Published in 2017 at "Future medicinal chemistry"

DOI: 10.4155/fmc-2017-0048

Abstract: Genetic variation in HIV poses a major challenge for prevention and treatment of the AIDS pandemic. Resistance occurs by mutations in the target proteins that lower affinity for the drug or alter the protein dynamics,… read more here.

Keywords: resistance genotype; hiv resistance; decoding hiv; resistance ... See more keywords