RT-qPCR Detection of Low-Copy HIV RNA with Yin-Yang Probes.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0138-9_3
Abstract: Accurate monitoring of low levels of viral load (the number of viral particles per milliliter of plasma) in HIV-infected patients is important in terms of evaluation of the progress of antiretroviral therapy. The general approach… read more here.
Keywords: hiv rna; detection; yin yang; detection low ... See more keywords
Changes in Days of Unhealthy Alcohol Use and Antiretroviral Therapy Adherence, HIV RNA Levels, and Condomless Sex: A Secondary Analysis of Clinical Trial Data
Sign Up to like & getrecommendations! Published in 2019 at "AIDS and Behavior"
DOI: 10.1007/s10461-019-02742-y
Abstract: In a sample of people with HIV (PWH) enrolled in an alcohol intervention trial and followed for 12 months, we examined the association of changes in days (i.e., decrease, increase, no change [reference]) of unhealthy drinking… read more here.
Keywords: hiv rna; hiv; days unhealthy; condomless sex ... See more keywords
Selective recognition of HIV RNA by dinuclear metallic ligands
Sign Up to like & getrecommendations! Published in 2018 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2018.06.003
Abstract: ABSTRACT We describe the development of dinuclear metallic ligands to target specific HIV RNA structures. Two series of dipyridinyl-N bridged dinuclear metal complexes were synthesized in moderate to good yields and their binding activities toward… read more here.
Keywords: dinuclear metallic; selective recognition; rna; metallic ligands ... See more keywords
Opioid use trajectory groups and changes in a physical health biomarker among HIV-positive and uninfected patients receiving opioid agonist treatment.
Sign Up to like & getrecommendations! Published in 2019 at "Drug and alcohol dependence"
DOI: 10.1016/j.drugalcdep.2019.06.014
Abstract: BACKGROUND Objective outcomes for measuring the physical health effects of substance use disorder treatment are needed. We compared the responsiveness of CD4, HIV-1 RNA and a biomarker index (VACS Index 2.0) to changes in opioid… read more here.
Keywords: use; treatment; hiv rna; health ... See more keywords
Carbon ink-based electrodes modified with nanocomposite as a platform for electrochemical detection of HIV RNA
Sign Up to like & getrecommendations! Published in 2021 at "Microchemical Journal"
DOI: 10.1016/j.microc.2021.106739
Abstract: Abstract This work reports a new and easy-to-use methodology for construction of screen-printed electrodes (SPE) based on carbon ink and its modification with 4-aminothiophenol (4-ATP) and gold nanoparticles for detection of HIV RNA. Morphological analysis… read more here.
Keywords: hiv rna; detection hiv; carbon ink;
Structure of the 30 kDa HIV-1 RNA Dimerization Signal by a Hybrid Cryo-EM, NMR, and Molecular Dynamics Approach.
Sign Up to like & getrecommendations! Published in 2018 at "Structure"
DOI: 10.1016/j.str.2018.01.001
Abstract: Cryoelectron microscopy (cryo-EM) and nuclear magnetic resonance (NMR) spectroscopy are routinely used to determine structures of macromolecules with molecular weights over 65 and under 25 kDa, respectively. We combined these techniques to study a 30 kDa HIV-1… read more here.
Keywords: molecular dynamics; structure kda; kda hiv; structure ... See more keywords
Elucidating the in vivo interactome of HIV-1 RNA by hybridization capture and mass spectrometry
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-16793-5
Abstract: HIV-1 replication requires myriad interactions between cellular proteins and the viral unspliced RNA. These interactions are important in archetypal RNA processes such as transcription and translation as well as for more specialized functions including alternative… read more here.
Keywords: hiv rna; hiv; rna; hybridization capture ... See more keywords
Nanoscale probing and imaging of HIV-1 RNA in cells with a chimeric LNA-DNA sensor.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d1nr08418f
Abstract: Real-time detection and nanoscale imaging of human immunodeficiency virus type 1 ribonucleic acid (HIV-1 RNA) in latently infected cells that persist in people living with HIV-1 on antiretroviral therapy in blood and tissue may reveal… read more here.
Keywords: hiv rna; dna sensor; hiv; lna dna ... See more keywords
Outcomes following detection of low level plasma HIV RNA in HIV-infected patients previously virologically suppressed on antiretroviral therapy: a retrospective observational study.
Sign Up to like & getrecommendations! Published in 2017 at "Sexual health"
DOI: 10.1071/sh16165
Abstract: BACKGROUND Progressively sensitive assays for plasma HIV RNA have led to increased detection of plasma HIV RNA between 20 and 200 copies/ml, known as low level viremia (LLV) when recurrent or persistent, in HIV-infected patients… read more here.
Keywords: detection; plasma hiv; hiv; hiv rna ... See more keywords
HIV-1 RNA and DNA genotyping drug resistance detection in patients with low-level viremia in Liangshan, China.
Sign Up to like & getrecommendations! Published in 2023 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2022.0140
Abstract: In this study, we characterized HIV-1 RNA and HIV-1 DNA genotyping drug resistance detection in patients with low-level viremia in Liangshan, China. Whole blood samples were collected from HIV/AIDS patients who had received anti-retroviral therapy… read more here.
Keywords: hiv rna; drug; dna; drug resistance ... See more keywords
Implementation of an HIV RNA Qualitative PCR Assay in an HIV Diagnostic Algorithm: A Single-Institution Experience.
Sign Up to like & getrecommendations! Published in 2023 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqad002
Abstract: OBJECTIVES Boston Medical Center (BMC) is a private, not-for-profit 514-bed academic medical center and legacy safety net hospital serving a diverse global patient population. BMC recently implemented a new HIV-1/HIV-2 Qualitative RNA PCR (HIV RNA… read more here.
Keywords: hiv; rna qual; algorithm; implementation hiv ... See more keywords