Achieving consistency in measures of HIV‐1 viral suppression across countries: derivation of an adjustment based on international antiretroviral treatment cohort data
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the International AIDS Society"
DOI: 10.1002/jia2.25776
Abstract: The third of the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90‐90‐90 targets is to achieve a 90% rate of viral suppression (HIV viral load read more here.
Keywords: antiretroviral treatment; suppression; adjustment; hiv viral ... See more keywords
A flexible nonlinear mixed effects model for HIV viral load rebound after treatment interruption.
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DOI: 10.1002/sim.8529
Abstract: Characterization of HIV viral rebound after the discontinuation of antiretroviral therapy is central to HIV cure research. We propose a parametric nonlinear mixed effects model for the viral rebound trajectory, which often has a rapid… read more here.
Keywords: rebound; hiv viral; viral rebound; viral load ... See more keywords
HIV-1 viral cores enter the nucleus collectively through the nuclear endocytosis-like pathway
Sign Up to like & getrecommendations! Published in 2020 at "Science China Life Sciences"
DOI: 10.1007/s11427-020-1716-x
Abstract: It is recognized that HIV-1 capsid cores are disassembled in the cytoplasm, releasing their genomes into the nucleus through nuclear pores, but there is also evidence showing the capsid (CA) exists in the nucleus. Whether… read more here.
Keywords: cores enter; hiv; hiv viral; viral cores ... See more keywords
A multi-center study comparing the analytical sensitivity and clinical concordance of three HIV-1 viral load assays.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of virological methods"
DOI: 10.1016/j.jviromet.2021.114373
Abstract: BACKGROUND HIV-1 viral load assays are essential tools for clinical management of people living with HIV-1. OBJECTIVES AND STUDY DESIGN We evaluated concordance between three assays: the cobas® HIV-1 test for use on the cobas®… read more here.
Keywords: cobas hiv; concordance; hiv viral; viral load ... See more keywords
HIV and viral hepatitis coinfection analysis using surveillance data from 15 US states and two cities
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DOI: 10.1017/s0950268818000766
Abstract: Abstract Coinfection with human immunodeficiency virus (HIV) and viral hepatitis is associated with high morbidity and mortality in the absence of clinical management, making identification of these cases crucial. We examined characteristics of HIV and… read more here.
Keywords: using surveillance; hepatitis; viral hepatitis; hiv viral ... See more keywords
Association of a 3' untranslated region polymorphism in proprotein convertase subtilisin/kexin type 9 with HIV viral load and CD4+ levels in HIV/hepatitis C virus coinfected women.
Sign Up to like & getrecommendations! Published in 2017 at "AIDS"
DOI: 10.1097/qad.0000000000001648
Abstract: OBJECTIVE To assess variation in genes that regulate cholesterol metabolism in relation to the natural history of HIV infection. DESIGN Cross-sectional and longitudinal analysis of the Women's Interagency HIV Study. METHODS We examined 2050 single… read more here.
Keywords: hiv viral; load cd4; viral load; hiv ... See more keywords
Chronic hepatitis C virus infection and subsequent HIV viral load among women with HIV initiating antiretroviral therapy
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DOI: 10.1097/qad.0000000000001745
Abstract: Objectives: One in four persons living with HIV is coinfected with hepatitis C virus (HCV). Biological and behavioral mechanisms may increase HIV viral load among coinfected persons. Therefore, we estimated the longitudinal effect of chronic… read more here.
Keywords: chronic hcv; hiv; hiv viral; among women ... See more keywords
Critical mechanistic features of HIV-1 viral capsid assembly
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DOI: 10.1101/2022.05.03.490470
Abstract: The maturation of HIV-1 capsid protein (CA) into a cone-shaped lattice encasing the condensed RNA genome is critical for viral infectivity. During HIV-1 maturation, CA can self-assemble into a wide range of capsid morphologies made… read more here.
Keywords: mechanistic features; critical mechanistic; features hiv; capsid formation ... See more keywords
Accuracy of self‐report of HIV viral load among people with HIV on antiretroviral treatment
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DOI: 10.1111/hiv.12477
Abstract: The aim of the study was to assess, among people living with HIV, knowledge of their latest HIV viral load (VL) and CD4 count. read more here.
Keywords: among people; hiv viral; viral load; accuracy self ... See more keywords
Food insecurity may lead to incomplete HIV viral suppression and less immune reconstitution among HIV/hepatitis C virus‐coinfected people
Sign Up to like & getrecommendations! Published in 2018 at "HIV Medicine"
DOI: 10.1111/hiv.12561
Abstract: The aim of this study was to determine the impact of food insecurity (FI) on HIV viral load and CD4 count among people coinfected with HIV and hepatitis C virus (HCV). read more here.
Keywords: hiv viral; hepatitis virus; hiv hepatitis; food insecurity ... See more keywords
Evaluation of the performance of a novel HIV-1 viral load assay for HIV quantification in China.
Sign Up to like & getrecommendations! Published in 2023 at "HIV medicine"
DOI: 10.1111/hiv.13473
Abstract: OBJECTIVES Our objective was to assess the HIV-1 quantification performance of the Livzon HIV-1 viral load (VL) assay and the Roche Cobas HIV-1 assay to evaluate an HIV-1 VL testing reagent for application in China.… read more here.
Keywords: quantification; hiv; viral load; correlation ... See more keywords