Upregulation of MicroRNA 711 Mediates HIV-1 Vpr Promotion of Kaposi's Sarcoma-Associated Herpesvirus Latency and Induction of Pro-proliferation and Pro-survival Cytokines by Targeting the Notch/NF-κB-Signaling Axis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Virology"
DOI: 10.1128/jvi.00580-18
Abstract: HIV-1 infection significantly increases the risk of KS and PEL in KSHV-infected individuals. Our previous study has shown that HIV-1 Vpr regulates the KSHV life cycle by targeting IκBα to activate NF-κB signaling through upregulating… read more here.
Keywords: survival cytokines; mir 711; hiv vpr; kshv ... See more keywords
Genetic Analysis of HIV-1 vpr Sequences from HIV-Infected Older Patients on Long Term Antiretroviral Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Current HIV research"
DOI: 10.2174/1570162x20666220705124341
Abstract: BACKGROUND Many HIV-infected individuals have achieved undetectable viral load and increased CD4 T cells counts due to success of antiretroviral therapy (ART). However, HIV continue to persist in resting T cells, monocytes/macrophages and other quiescent… read more here.
Keywords: hiv infected; vpr sequences; infected older; hiv vpr ... See more keywords