HIV-1 Vpu restricts Fc-mediated effector functions in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Cell reports"
DOI: 10.1101/2022.02.21.481308
Abstract: Non-neutralizing antibodies (nnAbs) can eliminate HIV-1-infected cells via antibody-dependent cellular cytotoxicity (ADCC) and were identified as a correlate of protection in the RV144 vaccine trial. Fc-mediated effector functions of nnAbs were recently shown to alter… read more here.
Keywords: hiv vpu; vpu restricts; mediated effector; vpu ... See more keywords
Decreased, Deformed, Defective—How HIV-1 Vpu Targets Peroxisomes
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DOI: 10.1128/mbio.00967-20
Abstract: Peroxisomes are found in essentially all eukaryotic cells and have been described as important hubs in innate sensing and the induction of type III interferons upon viral infection. Nevertheless, it remains poorly investigated how viral… read more here.
Keywords: innate sensing; vpu; hiv; hiv vpu ... See more keywords