Binding to DCAF1 distinguishes TASOR and SAMHD1 degradation by HIV-2 Vpx.
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DOI: 10.1371/journal.ppat.1009609
Abstract: Human Immunodeficiency viruses type 1 and 2 (HIV-1 and HIV-2) succeed to evade host immune defenses by using their viral auxiliary proteins to antagonize host restriction factors. HIV-2/SIVsmm Vpx is known for degrading SAMHD1, a… read more here.
Keywords: hiv vpx; degradation; tasor; vpx ... See more keywords