pH-sensitive Silk Fibroin Nanoparticles Encapsulating Β-Hydroxyisovalerylshikonin for Targeted Pancreatic Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2025 at "Current drug delivery"
DOI: 10.2174/0115672018342718241030070142
Abstract: BACKGROUND Pancreatic cancer is a highly malignant tumor with a poor prognosis, and current treatment methods have limited effectiveness. Therefore, developing new and more effective therapeutic strategies is crucial. This study aims to establish pH-responsive… read more here.
Keywords: cancer; hivs; nanoparticles encapsulating; silk fibroin ... See more keywords
β-Hydroxyisovaleryl-Shikonin Exerts an Antitumor Effect on Pancreatic Cancer Through the PI3K/AKT Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.904258
Abstract: Pancreatic cancer (PC) is marked with a low survival rate and lack of recognized effective treatment strategy. We investigated the antitumor effect of β-hydroxyisovaleryl-shikonin (β-HIVS) on PC and the associated working mechanism. Cell toxicity was… read more here.
Keywords: cell; pi3k akt; pancreatic cancer; hivs ... See more keywords