HIWI2 induces G2/M cell cycle arrest and apoptosis in human fibrosarcoma via the ROS/DNA damage/p53 axis.
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DOI: 10.1016/j.lfs.2022.120353
Abstract: AIMS Piwi, like RNA-mediated gene silencing 4 (PIWIL4) or HIWI2, are seen deregulated in human cancers and possibly play critical roles in tumorigenesis. It is unknown what role HIWI2 plays in the regulation of fibrosarcoma,… read more here.
Keywords: fibrosarcoma; apoptosis; cell cycle; hiwi2 ... See more keywords