HJURP interaction with the condensin II complex during G1 promotes CENP-A deposition
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DOI: 10.1091/mbc.e15-12-0843
Abstract: Condensin II interacts with human CENP-A chaperone HJURP and is present at centromeres in early G1. Condensin II, but not condensin I, is required for efficient CENP-A deposition in human cells. HJURP-induced chromatin decondensation at… read more here.
Keywords: hjurp interaction; hjurp; condensin; cenp deposition ... See more keywords
The expression, clinical relevance, and prognostic significance of HJURP in cholangiocarcinoma
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DOI: 10.3389/fonc.2022.972550
Abstract: Background Cholangiocarcinoma (CCA) is the malignancy originating from the biliary epithelium, including intrahepatic (iCCA), perihilar (pCCA), and distal (dCCA) CCA. The prognosis of CCA is very poor, and the biomarkers of different CCA subsets should… read more here.
Keywords: cca; clinical relevance; expression; relevance prognostic ... See more keywords
Unraveling the Role of Histone Variant CENP-A and Chaperone HJURP Expression in Thymic Epithelial Neoplasms
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DOI: 10.3390/ijms23158339
Abstract: Background: Recent advances demonstrate the role of chromatin regulators, including histone variants and histone chaperones, in cancer initiation and progression. Methods: Histone H3K4me3, histone variant centromere protein (CENP-A) and histone chaperones Holliday junction recognition protein… read more here.
Keywords: thymic epithelial; expression; hjurp; cenp ... See more keywords
HJURP Promotes Epithelial-to-Mesenchymal Transition via Upregulating SPHK1 in Hepatocellular Carcinoma
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DOI: 10.7150/ijbs.30904
Abstract: Holliday Junction Recognition Protein (HJURP) is involved in various cancers including hepatocellular carcinoma (HCC). Current studies have showed that HJURP is correlated with HCC proliferation. However, the role of HJURP in HCC Epithelial-to-Mesenchymal Transition remains… read more here.
Keywords: hepatocellular carcinoma; mesenchymal transition; upregulating sphk1; hjurp ... See more keywords